Salicylic acid biosynthesis is not from phenylalanine in <i>Arabidopsis</i>

Wu, Jie; Zhu, Wentao; Zhao, Qiao

doi:10.1111/jipb.13410

Cited by 46 publications

(28 citation statements)

References 32 publications

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“…It is well known that SA plays an important role in the defence response of plants against parasitic pathogens, and powdery mildew is a typical parasitic pathogen. In A. thaliana , about 90% of SA biosynthesis induced by pathogens or UV light is through the ICS pathway (Garcion et al, 2008; Niu et al, 2020; Wildermuth et al, 2001; Wu et al, 2019; Wu et al, 2022). In this study, we found that compared with PM, RL + PM treatment activated the expression of a series of genes in the SA synthesis pathway ( CmICS , CmPBS5 and CmEDS5.1 ) (Figure 2b, Supporting Information: Figure ) and promoted the accumulation of SA (Figure 2a).…”

Section: Discussionmentioning

confidence: 99%

PIF8‐WRKY42‐mediated salicylic acid synthesis modulates red light induced powdery mildew resistance in oriental melon

Wang

Xing

et al. 2023

Plant Cell & Environment

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Light signals and plant hormones are involved in regulating the growth, development and stress resistance of plants; however, it remains unclear whether light affects hormones and thus pathogen resistance in oriental melon. Here, we found that red light promoted salicylic acid (SA) accumulation and powdery mildew resistance by activating the transcription of CmICS, the key gene for SA biosynthesis, and silencing CmICS seriously weakened the induction effect of red light on powdery mildew resistance in oriental melon leaves. Further studies showed that red light induced the expression of CmWRKY42 under powdery mildew stress, and CmWRKY42 directly bound to the CmICS promoter to activate its expression and promote the accumulation of SA under red light. Furthermore, we found that PHYTOCHROME INTERACTING FACTOR 8 (PIF8), as a negative regulator of SA biosynthesis, inhibits CmWRKY42 transcriptional activation by binding to the CmWRKY42 promoter, and thus inhibits transcriptional activation of CmICS by CmWRKY42. Also, CmPIF8 binds to the CmICS promoter and directly inhibits its transcription. In conclusion, our study revealed a new molecular mechanism of the relationship between red light-SApowdery mildew resistance and provided a theoretical basis for resistance breeding of oriental melon.

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Section: Discussionmentioning

confidence: 99%

PIF8‐WRKY42‐mediated salicylic acid synthesis modulates red light induced powdery mildew resistance in oriental melon

Wang

Xing

et al. 2023

Plant Cell & Environment

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“…S1 B). However, Wu et al [ 13 ] recently found that phenylalanine could not synthesize SA (2-Hydroxybenzoic acid, 2-HBA), but synthesized 4-hydroxybenzoic acid (4-HBA), an isomer of SA. In this study, several DEGs were associated with signaling pathways such as JA/ethylene, SA, auxin, abscisic acid (ABA), and cytokinin (CTK), and JA may play a key role via negative regulation of α-linolenic acid metabolism.…”

Section: Discussionmentioning

confidence: 99%

Gene enrichment and co-expression analysis shed light on transcriptional responses to Ralstonia solanacearum in tomato

Shi

Shui

et al. 2023

BMC Genomics

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Background Tomato (Solanum lycopersicum) is both an important agricultural product and an excellent model system for studying plant-pathogen interactions. It is susceptible to bacterial wilt caused by Ralstonia solanacearum (Rs), and infection can result in severe yield and quality losses. To investigate which genes are involved in the resistance response to this pathogen, we sequenced the transcriptomes of both resistant and susceptible tomato inbred lines before and after Rs inoculation. Results In total, 75.02 Gb of high-quality reads were generated from 12 RNA-seq libraries. A total of 1,312 differentially expressed genes (DEGs) were identified, including 693 up-regulated and 621 down-regulated genes. Additionally, 836 unique DEGs were obtained when comparing two tomato lines, including 27 co-expression hub genes. A total of 1,290 DEGs were functionally annotated using eight databases, most of which were found to be involved in biological pathways such as DNA and chromatin activity, plant-pathogen interaction, plant hormone signal transduction, secondary metabolite biosynthesis, and defense response. Among the core-enriched genes in 12 key pathways related to resistance, 36 genotype-specific DEGs were identified. RT-qPCR integrated analysis revealed that multiple DEGs may play a significant role in tomato response to Rs. In particular, Solyc01g073985.1 (NLR disease resistance protein) and Solyc04g058170.1 (calcium-binding protein) in plant-pathogen interaction are likely to be involved in the resistance. Conclusion We analyzed the transcriptomes of both resistant and susceptible tomato lines during control and inoculated conditions and identified several key genotype-specific hub genes involved in a variety of different biological processes. These findings lay a foundation for better understanding the molecular basis by which resistant tomato lines respond to Rs.

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“…The means by which the PAL pathway promotes SA synthesis is still controversial. A recent study indicated that the PAL gene catalyzes phenylalanine to finally synthesize 4-hydroxybenzoic acid (4-HBA) rather than SA [ 30 ]. In any case, it is clear that BA is the precursor of SA.…”

Section: Sa Biosynthesis In Plantsmentioning

confidence: 99%

Emerging Roles of Salicylic Acid in Plant Saline Stress Tolerance

Yang

Zhou

Zhang

2023

IJMS

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One of the most important phytohormones is salicylic acid (SA), which is essential for the regulation of plant growth, development, ripening, and defense responses. The role of SA in plant–pathogen interactions has attracted a lot of attention. Aside from defense responses, SA is also important in responding to abiotic stimuli. It has been proposed to have great potential for improving the stress resistance of major agricultural crops. On the other hand, SA utilization is dependent on the dosage of the applied SA, the technique of application, and the status of the plants (e.g., developmental stage and acclimation). Here, we reviewed the impact of SA on saline stress responses and the associated molecular pathways, as well as recent studies toward understanding the hubs and crosstalk between SA-induced tolerances to biotic and saline stress. We propose that elucidating the mechanism of the SA-specific response to various stresses, as well as SA-induced rhizosphere-specific microbiome modeling, may provide more insights and support in coping with plant saline stress.

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Salicylic acid biosynthesis is not from phenylalanine in Arabidopsis

Cited by 46 publications

References 32 publications

PIF8‐WRKY42‐mediated salicylic acid synthesis modulates red light induced powdery mildew resistance in oriental melon

PIF8‐WRKY42‐mediated salicylic acid synthesis modulates red light induced powdery mildew resistance in oriental melon

Gene enrichment and co-expression analysis shed light on transcriptional responses to Ralstonia solanacearum in tomato

Emerging Roles of Salicylic Acid in Plant Saline Stress Tolerance

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