Salivary Biochemistry in Buffalo: The Legacy of Michael J. Levine

Scannapieco, Frank A.

doi:10.1177/154405910308200201

Cited by 3 publications

(2 citation statements)

References 41 publications

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“…He also made significant contributions to salivary research. He and his students were the first to purify salivary mucin (MG2) and the proline-rich glycoprotein and to characterize mucin structure and function, the interaction of salivary components with bacteria, salivary dysfunction, and the development of biologically based artificial saliva (Scannapieco, 2003).…”

Section: Prominent Faculty Membersmentioning

confidence: 99%

Oral Biology in Middle Age

Scannapieco

2014

J Dent Res

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In 1960, the first Department of Oral Biology in the United States dedicated to the conduct of research, graduate biomedical research education, and the provision of basic oral science education for the DDS curriculum was established at the University at Buffalo. In 1963, the Department organized the first PhD Program in Oral Biology in the United States. This PhD program has produced a large cadre of oral health researchers, many of whom have gone on to make major contributions to dental research and education. This article provides a brief history of the program, the context within which the program was organized and developed, and a description of some of the many faculty, students, and fellows associated with the program. Additionally, to celebrate the 50th anniversary of this program, a symposium, entitled "The Oral Microbiome, Immunity and Chronic Disease", was held on June 12-14, 2013, in Buffalo, New York. The proceedings are published online in Advances in Dental Research (2014, Vol. 26).

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Section: Prominent Faculty Membersmentioning

confidence: 99%

Oral Biology in Middle Age

Scannapieco

2014

J Dent Res

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“…While working at the State University of New York at Buffalo, Michael Levine spawned several important discoveries regarding salivary proteins and served as the mentor for the training of a platoon of combined DDS and PhD degreed individuals 75 . Levine and colleagues identified the importance of salivary proteins as part of the framework for bacterial adherence to the teeth by bacterial proteins interacting with specific domains within salivary proteins, forming a molecular "Velcro" for adhesion 76 .…”

Section: Saliva As a Diagnostic Fluidmentioning

confidence: 99%

Science Is the Fuel for the Engine of Technology and Clinical Practice

Snead¹,

Slavkin²

2009

The Journal of the American Dental Association

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The biological, chemical, behavioral and physical sciences provide the fuel for the engine of innovation and discovery that continuously improve the quality of the human condition. Dramatic breakthroughs in computer power derived from the digital revolution, provides extraordinary computational capacity for diagnostic imaging, bioinformatics (the science of information), and numerous aspects of how we practice dentistry in the 21st century. Moreover, the biological revolution with the elucidation of the structure of DNA, celebrated its 56th anniversary in May 1, provides the body of knowledge proving itself to be catalytic for discoveries that improve patient care---diagnostics, treatments and therapeutics, and new biomaterials. Humanity's most basic and recognizable characteristics are now understood through the elucidation of our genome and proteome 2, 3 the genes and the proteins they encode. We are now beginning to utilize "personalized" genetic predisposition and so much more. These and so many more "ways of knowing" continue to fuel advances in the scientific disciplines that support our dental profession and form the basis for new diagnostic tests, affording new therapies and procedures that improve the quality of life for our patients. And we are today on the thresh hold of stem cell biology applied to regenerative medicine and dentistry. We have entered an era when engineering biological solutions to the loss of tissues and organs as a consequence of disease are now realities.

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