Salivary Duct Carcinoma

Gilcrease, Michael Z.; Guzman-Paz, Manuel; Froberg, Kent; Pambuccian, Stefan E.

doi:10.1159/000332173

Cited by 24 publications

(4 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[2] Nevertheless, if cribriform groups are noted in a salivary gland aspirate, the diagnosis of salivary duct carcinoma should at least be considered. [7] However, in the present case, cribriform pattern was not noted cytologically. The absence of cribriform or papillary groups suggests an inconclusive diagnosis and the need to establish a differential diagnosis with other salivary gland tumors, in particular with adenocarcinoma not otherwise specified and high-grade mucoepidermoid carcinoma.…”

Section: Discussioncontrasting

confidence: 68%

A rare tumor of salivary gland: Diagnostic Dilemma on fine needle aspiration cytology

Agarwal

Kaushal

Bhardwaj

2017

J Cytol

View full text Add to dashboard Cite

Salivary gland cytopathology is a diagnostically challenging area with overlapping cytomorphological features between benign, malignant, and metastatic tumors. We report the case of 45-year-old male who presented with two swellings in right retroauricular and infraauricular region along with a palpable single right cervical lymph node. On ultrasonography of the neck, a possibility of malignant lesion was given. Contrast enhanced computed tomography of the head showed a large well-defined space occupying lesion in right temporooccipital region eroding the skull bone with both extra and intracranial extension. Fine needle aspiration was performed from both swellings and cervical lymph node. Based on cytological features and clinicoradiological examination, a possibility of metastasis from epithelial malignancy (adenocarcinoma) was suggested. The retroauricular region swelling was excised, and a diagnosis of salivary duct carcinoma was given on histopathology. In this article, we discuss the diverse presentation, cytomorphological features, and differential diagnosis of this rare salivary gland tumor.

show abstract

Section: Discussioncontrasting

confidence: 68%

A rare tumor of salivary gland: Diagnostic Dilemma on fine needle aspiration cytology

Agarwal

Kaushal

Bhardwaj

2017

J Cytol

View full text Add to dashboard Cite

show abstract

“…The presence of cribriform, papillary, and comedo patterns, which are best seen on cell block should alert the pathologist to the possibility of salivary duct carcinoma. [45] These features are not seen in any of the above-mentioned tumors. The papillary cystic variant of acinic cell carcinoma (ACC) may exhibit a papillary pattern.…”

Section: Discussionmentioning

confidence: 97%

“…[5] The apocrine features of salivary duct carcinoma may mislead to a diagnosis of oncocytic neoplasms. [45] Salivary duct carcinoma shows a higher nuclearcytoplasmic ratio, less granular cytoplasm, and many three-dimensional clusters. Warthin's tumor, with nuclear atypia, and paucity of lymphoid cells in the background may be mistaken for salivary duct carcinoma.…”

Section: Discussionmentioning

confidence: 99%

Salivary duct carcinoma of parotid gland

Kinnera

Mandyam

Chowhan

et al. 2009

J Oral Maxillofac Pathol

View full text Add to dashboard Cite

A 40-year old male presented with rapidly growing swelling in the right parotid region. Based on the fine needle aspiration cytology report of adenocarcinoma not otherwise specified, superficial parotidectomy was performed, which showed the features of salivary duct carcinoma by histopathological examination. The smears were reviewed to identify the potential pitfalls in the cytological diagnosis of salivary duct carcinoma.

show abstract

“…The individual cells are large, monomorphic to pleomorphic, and polygonal to cuboidal, with abundant, finely granular cytoplasm (Figure 5 ). Squamoid and oncocyte-like appearances are also seen [ 8 ]. Due to similar nature of salivary duct carcinoma and breast ductal carcinoma, over-expression of androgen receptor, human epidermal growth factor receptor 2 (HER-2)/neu proto-oncogene has also been studied (Figure 6 ).…”

Section: Discussionmentioning

confidence: 99%

Clinicopathological Behavior and Treatment-related Outcome of Rare Salivary Duct Carcinoma: The Shaukat Khanum Memorial Cancer Hospital Experience

Anwer

Faisal

Adeel

et al. 2018

Cureus

View full text Add to dashboard Cite

BackgroundSalivary gland tumors are rare salivary gland malignancies with resemblance to ductal breast carcinoma. We have described clinicopathological behavior and treatment outcomes of this rare malignancy.MethodsSalivary duct carcinoma patients treated from 2010 to 2015 were retrospectively analyzed for clinicopathological characteristics and treatment-related outcomes of the disease.ResultsA total of 12 patients with salivary duct carcinoma were included in the study. All were males with mean age of 52.58 ± 13.43. Parotid gland was the most commonly involved major salivary gland while buccal mucosa and anterior tongue were most common oral cavity sub-sites involving minor salivary glands. The disease-free survival was 75% at 10 months and 25% at 20 months. The mean follow-up time was 12 months. There were three local recurrences and one distant metastasis.ConclusionSalivary duct carcinoma is a locally aggressive tumor with tendency for local recurrence and distant metastasis. Adverse features such as perineural invasion, extra-capsular spread and advanced nodal disease may worsen prognosis.

show abstract

Salivary Duct Carcinoma

Cited by 24 publications

References 12 publications

A rare tumor of salivary gland: Diagnostic Dilemma on fine needle aspiration cytology

A rare tumor of salivary gland: Diagnostic Dilemma on fine needle aspiration cytology

Salivary duct carcinoma of parotid gland

Clinicopathological Behavior and Treatment-related Outcome of Rare Salivary Duct Carcinoma: The Shaukat Khanum Memorial Cancer Hospital Experience

Contact Info

Product

Resources

About