Salivary duct carcinoma of the parotid gland case report and review of the literature.

Abstract

Salivary duct carcinoma is an uncommon neoplasm which was first described by Kleinsasser et al. in 1968. They pointed out the histologic resemblance of this tumor to ductal carcinoma of the breast and termed it salivary duct carcinoma. Since then, about sixty cases, including some with

Cystic Salivary Duct Carcinoma Penetrated by Facial Nerve

“…It typically has solid features and when it occurs in the parotid gland, it sometimes invade the facial nerve and induce facial nerve paralysis. 4 7 However, in our case, the salivary duct carcinoma underwent a cystic change, and the facial nerve passed through the cyst. However, the patient had no symptoms of facial nerve palsy.…”

“…Hormone therapy has been applied as an adjuvant treatment in some cancers, but its efficacy in salivary duct carcinoma has not yet been demonstrated. 4 …”

“…Hormone therapy has been applied as an adjuvant treatment in some cancers, but its efficacy in salivary duct carcinoma has not yet been demonstrated. 4 Salivary duct carcinoma typically presents clinically as a painless, rapidly growing mass, which develops aggressively with the possibility of early distant metastasis and local recurrence. It typically has solid features and when it occurs in the parotid gland, it sometimes invade the facial nerve and induce facial nerve paralysis.…”

“…It is highly malignant, and nearly half of the patients die from the disease within 5 years. 4 Wide surgical resection and postoperative radiotherapy are necessary to treat salivary duct carcinoma. 5 Despite these, its prognosis remains poor.…”