Salivary estradiol and testosterone in filipino men: Diurnal patterns and relationships with adiposity

Gettler, Lee T.; McDade, Thomas W.; Feranil, Alan B.; Agustin, Sonny S.; Kuzawa, Christopher W.

doi:10.1002/ajhb.22528

Cited by 12 publications

(17 citation statements)

References 67 publications

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“…This represents the early evening period when daytime work concludes, and individuals return from the river and fields to shift their attention toward household tasks. We specifically designed our study to collect repeated evening samples from individuals because T's well‐characterized diurnal curve typically reaches its nadir by late afternoon and remains at that level through the evening, until sleep commences (Gettler, McDade, Feranil, Agustin, & Kuzawa, ; Mezzullo et al, ; Schmid, Hallschmid, Jauch‐Chara, Lehnert, & Schultes, ). This design thus helped our small research team minimize between‐subject and between‐day variability in T that might be attributable to the time of sampling.…”

Section: Methodsmentioning

confidence: 99%

Mothers' and fathers' joint profiles for testosterone and oxytocin in a small‐scale fishing‐farming community: Variation based on marital conflict and paternal contributions

et al. 2019

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Introduction Testosterone and oxytocin are psychobiological mechanisms that interrelate with relationship quality between parents and the quantity and quality of parenting behaviors, thereby affecting child outcomes. Their joint production based on family dynamics has rarely been tested, particularly cross‐culturally. Methods We explored family function and salivary testosterone and oxytocin in mothers and fathers in a small‐scale, fishing‐farming society in Republic of the Congo. Fathers ranked one another in three domains of family life pertaining to the local cultural model of fatherhood. Results Fathers who were viewed as better providers had relatively lower oxytocin and higher testosterone than men seen as poorer providers, who had lower testosterone and higher oxytocin. Fathers also had higher testosterone and lower oxytocin in marriages with more conflict, while those who had less marital conflict had reduced testosterone and higher oxytocin. In contrast, mothers in conflicted marriages showed the opposite profiles of relatively lower testosterone and higher oxytocin. Mothers had higher oxytocin and lower testosterone if fathers were uninvolved as direct caregivers, while mothers showed an opposing pattern for the two hormones if fathers were seen as involved with direct care. Conclusions These results shed new light on parents' dual oxytocin and testosterone profiles in a small‐scale society setting and highlight the flexibility of human parental psychobiology when fathers' roles and functions within families differ across cultures.

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Section: Methodsmentioning

confidence: 99%

Mothers' and fathers' joint profiles for testosterone and oxytocin in a small‐scale fishing‐farming community: Variation based on marital conflict and paternal contributions

et al. 2019

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“…The relevant studies that have examined these questions in relation to life history status or among fathers do not align with our results. They found no adiposity differences based on parenting status in spite of fathers’ lower T [70], no relationship between adiposity and fathers’ T production across the day [31], or elevated adiposity and lower T among fathers compared to non-fathers but not linkages between T and body fat [22]. Given that there are few studies in this area, it is unclear what accounts for this variation across contexts.…”

Section: Discussionmentioning

confidence: 99%

“…Meanwhile, more naturalistic, observational studies show more modest support as well as null results, and a recent study of subsistence agriculturalists suggests that human strength and muscularity might be decoupled from T in the context of routine demanding physical exertion [22, 27]. When considering the notion that lower T promotes investment in energy stores, there are a number of well-documented bidirectional physiological pathways through which reduced T and elevated adiposity tend to coincide, within individuals [31–33]. For example, higher T prevents recruitment of adipose precursor cells, contributes to fat cells being utilized as energy substrates, and diverts metabolic resources towards building skeletal muscle, which itself then carries further basal energetic costs [33].…”

Section: Background and Objectivesmentioning

confidence: 99%

“…For example, higher T prevents recruitment of adipose precursor cells, contributes to fat cells being utilized as energy substrates, and diverts metabolic resources towards building skeletal muscle, which itself then carries further basal energetic costs [33]. Meanwhile, in societies in which energetic abundance and sedentary lifestyles are common, men with greater adiposity often have reduced circulating T because adipose tissue converts (aromatizes) T to estradiol, and there is also evidence that obese men experience more rapid clearance of T from the body [31, 32]. …”

Section: Background and Objectivesmentioning

confidence: 99%

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Adiposity, CVD risk factors and testosterone

Gettler

Sarma

Gengo

et al. 2017

Evolution, Medicine, and Public Health

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Background and objectivesIn many settings, partnered, invested fathers have lower testosterone than single men or fathers who are not involved in caregiving. Reduced testosterone has been identified as a risk factor for multiple chronic diseases, and men’s health also commonly varies by life history status. There have been few tests of whether variation in testosterone based on partnering and parenting has implications for men’s health.MethodologyWe analysed data from a US population-representative sample (NHANES) of young-to-middle aged US men (n = 875; mean age: 29.8 years ± 6.0 [SD]). We tested for life history status differences in testosterone, adiposity levels and biomarkers of cardiovascular disease (CVD)-risk (HDL cholesterol; triglycerides; white blood cell count [WBC]).ResultsPartnered men residing with children (RC) had lower testosterone and elevated abdominal adiposity compared to never married men not residing with children. While they did not significantly differ for WBC or triglycerides, partnered RC men also had comparatively lower HDL. Partnered RC males’ lower testosterone accounted for their relatively elevated adiposity, but testosterone, adiposity, and health-related covariates did not explain their relatively reduced HDL.Conclusions and implicationsOur results linking life history status-based differences in testosterone and adiposity, alongside our complementary HDL findings, indicate that testosterone-related psychobiology might have implications for partnered RC men’s CVD risk in the US and other similar societal settings. These types of socially contextualized observations of men’s health and physiological function particularly merit incorporation in clinical discussions of fatherhood as a component of men’s health.

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“…E2 plays a negative feedback role within the hypothalamic‐pituitary‐gonadal axis (i.e., contributing to reduced T production), promotes adipose tissue accumulation in some areas on the body, is converted from T by adipose tissue (aromatization), and also has immunomodulatory functions. Thus, E2 is a hormone that is potentially relevant to life history trade‐offs between costly forms of reproductive effort and survival/maintenance and also to questions regarding fatherhood, marriage, and men's health (Bribiescas, ; Gettler et al, ; Gettler, McDade, Feranil, Agustin, & Kuzawa, ; Raven, de Jong, Kaufman, & de Ronde, ).…”

Section: Introductionmentioning

confidence: 99%

Fatherhood and psychobiology in the Philippines: Perspectives on joint profiles and longitudinal changes of fathers' estradiol and testosterone

Gettler

Kuo

Bechayda

2018

American J Hum Biol

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Objectives: Research on the psychobiology of partnering and fathering has focused on testosterone (T), oxytocin, and prolactin (PRL) as mechanisms that potentially mediate life history trade-offs related to those roles. Less is known about other hormones that might be responsive to life history transitions and implicated in fathering, such as estradiol (E2). We examined how E2 changed during the transition to marriage and fatherhood, its correlation with fathers' caregiving, and its joint within-individual production with other hormones (T, PRL). Methods: Data were collected from a total of 913 Filipino men (aged 25.9 years AE 0.3 SD at follow-up) enrolled in a longitudinal cohort study. Morning saliva samples collected at baseline (2005) and follow-up (2009) were assayed for T and E2 (n = 329), dried blood spots from baseline were assayed for PRL. Fathers reported on caregiving in 2009. Results: When compared with men who remained single non-fathers over the study period, men who became married residential fathers experienced larger declines in E2. This effect was non-significant when we controlled for longitudinal changes in T. E2 was not significantly related to fathers' caregiving, controlling for T. In cross-sectional analyses for PRL, T, and E2, married residential fathers exhibited within-individual profiles of reduced T and elevated PRL, whereas single nonfathers exhibited the opposite profile of elevated T and reduced PRL. Conclusions: Our findings point to the need for future research to consider the mutually regulatory dynamics and/or combinatorial implications of multiple physiological axes acting within individuals to underpin life history trade-offs and behavioral strategies.

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Salivary estradiol and testosterone in filipino men: Diurnal patterns and relationships with adiposity

Cited by 12 publications

References 67 publications

Mothers' and fathers' joint profiles for testosterone and oxytocin in a small‐scale fishing‐farming community: Variation based on marital conflict and paternal contributions

Mothers' and fathers' joint profiles for testosterone and oxytocin in a small‐scale fishing‐farming community: Variation based on marital conflict and paternal contributions

Adiposity, CVD risk factors and testosterone

Fatherhood and psychobiology in the Philippines: Perspectives on joint profiles and longitudinal changes of fathers' estradiol and testosterone

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