Salivary Gland Like Breast Carcinoma/Adenoid Cystic Carcinoma: Case Report

Abstract

Adenoid cystic carcinoma of the breast constitutes approximately 0.1% of all breast tumors. They can be located in the trachea, bronchus, cervix, lacrimal gland, and skin as well as the breast. Tumors in the breast have better prognoses compared to those in other locations. The diagnosis and treatment planning of this tumor is challenging due to its rare incidence. In this article, we presented a case that was diagnosed with adenoid cystic carcinoma of the breast upon pathology evaluation.A 59-year-old female patient was admitted to our clinic due to a mass in her right breast. Her mammography revealed a 1 cm in diameter mass in the upper outer quadrant of the right breast, which was classified as BIRADS 4C (Breast Imaging Reporting and Data System). On magnetic resonance imaging (MRI) the lesion was also reported as BIRADS 4C. The patient underwent breast conserving surgery (BCS), and the pathology result was reported as adenoid cystic carcinoma of the breast. The patient received chemo-radiotherapy in the postoperative period.Adenoid cystic carcinoma of the breast has been first described in the salivary glands. They can be confused with benign lesions both on physical and radiological examinations. Sentinel lymph node biopsy (SLNB) can be used since axillary metastases are rare. Local recurrence and distant metastases are also very rare. Usually, BCS followed by radiotherapy is adequate to obtain local control. In selected patients with a poor prognosis, chemotherapy and hormonal therapy should be added to the treatment.

The role of radiotherapy (RT) in the treatment of Adenoid Cystic Carcinoma of the Breast: case report of RT retreatment and literature review

“…Our clinical review results are reported in (Table 1). Mean LRFS reported by case reports was 24 months (range 20-48) [3,4,8,[10][11][12]. Mean DFS reported by case series and retrospective series was 87.9% (range 69-100%) [2,5,[13][14][15][16].…”

“…Mean DFS reported by case series and retrospective series was 87.9% (range 69-100%) [2,5,[13][14][15][16]. Mean OS reported in case reports was 30 months (range 12-84) [3,4,8,[10][11][12]. Mean 5-years OS reported in retrospective series was 89.7% [2,16,17].…”

An Observational Study on Cutaneous Appendageal Tumours with Pilar Differentiation

“…These tumors can differentiate in the direction of any of the four types of cutaneous appendages i.e., eccrine sweat glands, apocrine sweat glands, sebaceous glands and hair follicles. [3] They are often difficult to diagnose clinically and histopathology usually provides diagnostic confirmation. [4] Hair Follicle: Hair follicles begin to develop early during the fetal period, mainly around the 9thand 12thweek of gestation.…”