Salivary gland of the tick vector (R. appendiculatus) of East Coast fever. I. Ultrastructure of the type III acinus

Fawcett, Don W.; Doxsey, Stephen; Büscher, G.

doi:10.1016/0040-8166(81)90002-1

Cited by 62 publications

(29 citation statements)

References 15 publications

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“…These cells are similar to the f-cells described by Fawcett et al (1981) in the type II glandular acinus of Rhipicephalus appendiculatus. Spirochetes in the large extracellular spaces formed by this convoluted membrane system appear undistorted in size and shape (Fig.…”

Section: Borrelia Burgdorferi In the Salivary Glandssupporting

confidence: 84%

“…The spirochetes easily pass through the 25 intercellular spaces of the salivary acini and are able to pass through even the closely opposed cell membranes along the luminal zurface of the glandular acini. During feeding the cells of the glandular acini proliferate and secrete their granules; some then degenerate and some metamorphaose to take on an osmoregulatory function (Fawcett et al 1981). It is conceivable that during these cellular events the spirochetes may readily pass through into the lumen of the acinus.…”

Section: Discussionmentioning

confidence: 99%

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Determinants of Infectivity of Pathogens in Vector Ticks

Spielman¹

1990

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Section: Borrelia Burgdorferi In the Salivary Glandssupporting

confidence: 84%

Section: Discussionmentioning

confidence: 99%

Determinants of Infectivity of Pathogens in Vector Ticks

Spielman¹

1990

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“…Additionally, small numbers of electron‐dense inclusions (100–500 nm) are randomly distributed throughout these granules. Similar to d‐cells, the e‐cells in males are active for longer than in females; in the latter the cells regress after exocytosis of their secretory products during attachment (Fawcett et al ., 1981, 1986). …”

Section: Histochemistry and Electron Microscopy Of The Intracellular mentioning

confidence: 99%

“…They are less electron‐dense than the granules in a‐ and d‐cells and spherical or ovoid in shape (Fawcett, Doxsey & Buscher, 1981). At lower magnifications, the granules appear amorphous but higher resolution reveals close packaging of subunits (50–100 nm) within a denser substance, giving the granules a fine reticular pattern.…”

Section: Histochemistry and Electron Microscopy Of The Intracellular mentioning

confidence: 99%

Tick attachment cement – reviewing the mysteries of a biological skin plug system

et al. 2017

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The majority of ticks in the family Ixodidae secrete a substance anchoring their mouthparts to the host skin. This substance is termed cement. It has adhesive properties and seals the lesion during feeding. The particular chemical composition and the curing process of the cement are unclear. This review summarizes the literature, starting with a historical overview, briefly introducing the different hypotheses on the origin of the adhesive and how the tick salivary glands have been identified as its source. Details on the sequence of cement deposition, the curing process and detachment are provided. Other possible functions of the cement, such as protection from the host immune system and antimicrobial properties, are presented. Histochemical and ultrastructural data of the intracellular granules in the salivary gland cells, as well as the secreted cement, suggest that proteins constitute the main material, with biochemical data revealing glycine to be the dominant amino acid. Applied methods and their restrictions are discussed. Tick cement is compared with adhesives of other animals such as barnacles, mussels and sea urchins. Finally, we address the potential of tick cement for the field of biomaterial research and in particular for medical applications in future.

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“…In contrast, platelets have only two to six mitochondria per cell [7]. A living species genome is relatively stable during the life span of the organism, whereas its gene expression profiles vary dramatically and are tissue dependent [8,9]. Since mitochondrial number is tissue-dependant and most their proteins rely on the gene expression status in the resided tissues, a question thus is raised whether a mitochondrion in a tissue owns its specific proteome.…”

mentioning

confidence: 99%

Proteomic survey towards the tissue-specific proteins of mouse mitochondria

Wang

Sun

et al. 2011

Sci. China Life Sci.

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Mitochondrion plays the key functions in mammalian cells. It is believed that mitochondrion exerts the common biologic functions in many tissues, but also performs some specific functions correspondent with tissues where it is localized. To identify the tissue-specific mitochondrial proteins, we carried out a systematic survey towards mitochondrial proteins in the tissues of C57BL/6J mouse, such as liver, kidney and heart. The mitochondrial proteins were separated by 2DE and identified by MALDI-TOF/TOF MS. Total of 87 unique proteins were identified as the tissue-specific ones, and some representatives were further verified through ICPL quantification and Western blot. Because these issue-specific proteins are coded from nuclear genes, real-time PCR was employed to examine the mRNA status of six typical genes found in the tissues.With combining of the expression data and the co-localization images obtained from confocal microscope, we came to the conclusion that the tissue-specifically mitochondrial proteins were widely distributed among the mouse tissues. Our investigation, therefore, indeed provides a solid base to further explore the biological significance of the mitochondrial proteins with tissue-orientation.

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Salivary gland of the tick vector (R. appendiculatus) of East Coast fever. I. Ultrastructure of the type III acinus

Cited by 62 publications

References 15 publications

Determinants of Infectivity of Pathogens in Vector Ticks

Determinants of Infectivity of Pathogens in Vector Ticks

Tick attachment cement – reviewing the mysteries of a biological skin plug system

Proteomic survey towards the tissue-specific proteins of mouse mitochondria

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