Salivary gland scintigraphy—a suitable substitute for sialography?

Pilbrow, W. J.; Brownless, S. M.; Cawood, J.I.; Dynes, A.; Hughes, Justin; Stockdale, H. R.

doi:10.1259/0007-1285-63-747-190

Cited by 104 publications

(7 citation statements)

References 5 publications

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“…Scintigraphic changes correlate well with salivary scintigraphic abnormalities [9, 10]and histopathological changes [11, 12]. With salivary scintigraphy, the major salivary glands can be examined simply, noninvasively, simultaneously, and continuously.…”

Section: Introductionmentioning

confidence: 99%

Evidence for Decreased Salivary Function in Patients with Reflux Esophagitis

Kao

Ho²,

ChangLai³

et al. 1999

Digestion

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It has been speculated that impaired salivary flow contributes to abnormal acid clearance of the esophagus in gastroesophageal reflux and results in reflux esophagitis (RE). To test this hypothesis, salivary functions were measured by quantitative salivary scintigraphies in patients with RE and in age- and sex-matched controls for comparison. Nineteen patients with RE and 36 healthy volunteers were enrolled in the study. After an intravenous injection of 5 mCi Tc-99m pertechnetate, sequential images of 1 min/frame were acquired for 30 min. The 1- and 15-min uptake ratios (UR) of the tracer in the four major salivary glands over the backgrounds were calculated. Saliva excretion was stimulated by 1 tablet of 200 mg ascorbic acid given orally 15 min after injection of the tracer, then the maximal excretion ratios (ER) of the four major salivary glands were calculated for the sialagogue stimulation. RE patients had lower values of 1st and 15th min UR and maximal ER than controls in the 4 major salivary glands. Poor salivary functions which represented a decrease in both UR and ER for patients with RE have been confirmed by quantitative salivary scintigraphy in this study.

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Section: Introductionmentioning

confidence: 99%

Evidence for Decreased Salivary Function in Patients with Reflux Esophagitis

Kao

Ho²,

ChangLai³

et al. 1999

Digestion

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“…The uptake in the parotid and submandibular glands is equal to or greater than that in the thyroid (PILBROW et al 1990;SHIRAZI 1996). As SGI is both a functional and a morphological test, it may be indicated in malignancy of the gland.…”

Section: Salivary Gland Imagingmentioning

confidence: 99%

Trends in Contrast Media

Thomsen¹,

Müller²,

Mattrey³

et al. 1999

Medical Radiology

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“…Administered 99mTcO4− (Figure 2) is taken up by the salivary glands through NIS, similar to Cl−. Thus, intravenously administered 99mTcO4− accumulates mainly in the parotid and submandibular glands and is excreted into saliva [1]. After the accumulation of the radionuclide, loading of citric acid, such as lemon juice, stimulates the secretion of saliva, which indicates salivary gland function.…”

Section: Salivary Gland Scintigraphy 21 Mechanism Of Uptakementioning

confidence: 99%

Approach to Diagnosis of Salivary Gland Disease from Nuclear Medicine Images

Nakayama¹,

Okizaki²,

Nakajima³

et al. 2019

Salivary Glands - New Approaches in Diagnostics and Treatment

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Nuclear medicine images can help in the diagnosis and assessment of some salivary disorders. 99mTcO4−, gallium-67-citrate scintigraphy will be an indication of the function of salivary gland together and it will be used for the diffuse diseases such as sialadenitis, Sjögren's syndrome, sarcoidosis, glossopharyngeal paralysis, and irradiation. It is also effective for distinguishing benign tumor legion with Warthin's tumor and others. Moreover, fluorodeoxyglucose positron emission tomography (FDG-PET) is an indispensable modality for determining the localization, focal lesions, and staging of many malignant tumors, the fluorodeoxyglucose (FDG) accumulation is visually and semiquantitatively assessed using the standardized uptake value (SUV), which is the ratio of uptake to the injected dose per unit body weight. Also for radioactive iodine therapy, attention should be paid to adverse reactions. It is important to note that acute/chronic salivary gland disorders are associated with radioiodine therapy for the treatment of postoperative thyroid cancer. Coordination among healthcare providers including nurses, radiological technologists, and doctors of all departments involved in treatment is important for achieving effective outcomes.

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Salivary gland scintigraphy—a suitable substitute for sialography?

Cited by 104 publications

References 5 publications

Evidence for Decreased Salivary Function in Patients with Reflux Esophagitis

Evidence for Decreased Salivary Function in Patients with Reflux Esophagitis

Trends in Contrast Media

Approach to Diagnosis of Salivary Gland Disease from Nuclear Medicine Images

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