2022
DOI: 10.1016/j.jtos.2022.07.013
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Salivary gland transplantation for dry eye disease: Indications, techniques, and outcomes

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Cited by 16 publications
(9 citation statements)
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“…Thus, the microvascular anastomosis could also serve as guidance for nerves regrowing into the lacrimal gland graft. In addition, we found in biopsies of submandibular glands after free autotransplantation that parasympathetic ganglion cells survive in the grafts for many years and provide an autonomous source of neural stimulation to the secretory acinar cells [ 14 ]. From free submandibular gland transplants, we have learned that the grafts remain viable despite complete separation from their normal nerve supply and show an increasing secretory activity over months with excellent long-term functionality [ 15 ].…”
Section: Discussionmentioning
confidence: 99%
“…Thus, the microvascular anastomosis could also serve as guidance for nerves regrowing into the lacrimal gland graft. In addition, we found in biopsies of submandibular glands after free autotransplantation that parasympathetic ganglion cells survive in the grafts for many years and provide an autonomous source of neural stimulation to the secretory acinar cells [ 14 ]. From free submandibular gland transplants, we have learned that the grafts remain viable despite complete separation from their normal nerve supply and show an increasing secretory activity over months with excellent long-term functionality [ 15 ].…”
Section: Discussionmentioning
confidence: 99%
“…Nevertheless, it has limited popularity as it may often be accompanied by excessive tearing, and this type of surgery has low reproducibility [ 78 ]. Epiphora is rarely observed following minor salivary gland transplantation compared with submandibular gland transplantation [ 80 ].…”
Section: Managementmentioning
confidence: 99%
“…Similar fluorescein-based test can be used for examining labial salivary glands in diagnosing SS patients and evaluate transplanted minor salivary glands. [ 34 , 35 ]…”
Section: Examination Techniques For Lacrimal Gland Functionmentioning
confidence: 99%