Salivary levels of Interleukin-6 and Tumor Necrosis Factor-alpha in girls aged 7–17 years practicing volleyball

Peres, Carolina da Silva; Gava, Roberta Pratti; Zen, Igor; Correa, Julio Cesar Molina; Seixas, Gabriela Fleury; Silva, Carla Cristiane; Garbelini, Cássia Cilene Dezan; Ramos, Solange de Paula

doi:10.1016/j.apunts.2019.07.003

Cited by 6 publications

(5 citation statements)

References 47 publications

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“…Salivary levels of IL-6 and IL-8 were significantly higher in smokers with dental caries compared with control (p<0.05)[Table 2] . The levels of salivary cytokines are elevated as a result of disturbances in the oral cavity, and these results are in line with previous studies (13,14) . Also, these results were confirmed by the Kurtis et al where they found that high levels of IL-6 in dental caries patients lead to fewer broblasts and osteoblasts.…”

Section: Discussionsupporting

confidence: 92%

“…Concentrations of salivary IL-6, IL-8 and TNF-α were not affected by periodontal health.No statistically significant difference in periodontal health, assessed by CPITN, were observed between the groups (p=0.413) [Table 1]. These results are consistent with other studies (1,14) . One study indicated that elevated CRP levels were a risk factor for developing one type of cancer.…”

Section: Discussionsupporting

confidence: 88%

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Salivary levels of Interleukin-6, Interleukin-8 and Tumor Necrosis Factor-alpha in Smokers Aged 35-46 Years with Dental Caries Disease

2020

MLU

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Introduction: Dental caries is one of the most common infectious diseases prevalent in the oral cavity, and it is an inflammatory disease with a multi-factor etiology. IL-6, IL-8, and TNF-α are two types of cytokines that are major mediators of acute inflammation, and are necessary for the development of specific immune responses.Objective: The present study aimed to assess the level of pro-inflammatory cytokines (IL-6,IL-8,and TNF-α) in the saliva of smokers with dental caries and the control (non-smokers) according to different age, BMI,and sex. Materials and Method:Whole saliva from 32 smokers aged 35-46 years with dental caries and 16 healthy subjects, to measure IL-6,IL-8, and TNF-a levels by enzyme immunoassay (ELISA). Results:The mean BMI, age, and sex between the experimental group and the control group were similar, were not statistically significant (p=0.466, p=0.240, p=0.455), respectively while, there were a significant difference in CRP between the two groups (p=0.037).Concentrations of salivary IL-6, IL-8 and TNF-α were not affected by periodontal health. No statistically significant difference in periodontal health, assessed by CPITN, were observed between the groups (p=0.413). Salivary levels of IL-6 and IL-8 were significantly higher in smokers with dental caries compared with control (p<0.05).Salivary levels of IL-6 and IL-8 were increased significantly in smokers with dental caries compared with control (p<0.05). No significant differences in salivary TNF-α in dental caries patients compared to control (p=0.063). The correlation between TNF-a, CRP, age, sex, and BMI with IL-8 were positive and statistically significant(p=0.01, p=0.036, p=0.009, p=0.007, and p=0.005), respectively. Th ere was no significant correlation between IL-6 and TNF-a cytokines and other parameters, except for a positive association with CRP levels (p=0.006, p=0.043), respectively. Conclusions:These data indicate links between production of tumor necrosis factor-alpha (TNF-a), interleukin-6 (IL-6), and Interleukin-8 (IL-8)in smokers' saliva and dental caries disease. Also,the existence of a statistically significant positive correlation between TNF-a,age, gender, and BMI with IL-8.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 88%

Salivary levels of Interleukin-6, Interleukin-8 and Tumor Necrosis Factor-alpha in Smokers Aged 35-46 Years with Dental Caries Disease

2020

MLU

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“…Salivary cytokine levels were elevated due to disorders of the oral cavity ( Table 2 ), and these results were consistent with previous studies. 13 , 14 In our study, the mean salivary IgA rate was not significant, while the IL-1β rate was statistically different between the dental caries group and healthy subjects. Gomes et al 25 noted that salivary IL-1β and TNF-α levels increase in periodontal disease and are associated with the onset and increased severity of the disease, and that their levels decrease after treatment.…”

Section: Discussioncontrasting

confidence: 61%

“…These results are in agreement with other studies. 13 , 14 A previous study indicated that high levels of CRP are a risk factor for one type of cancer. Therefore, high levels of CRP before surgery can be considered an undesirable diagnostic indicator.…”

Section: Discussionmentioning

confidence: 99%

Correlation between salivary immunoglobulin A and interleukin-1beta in smokers with dental caries

et al. 2023

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Introduction. Dental caries is one of the most common infectious diseases of the oral cavity, and is an inflammatory disease caused by several factors. Interleukin-1β (IL-1β) is a major mediator of acute inflammation and essential for the development of specific immune responses. The objective of this study was to assess the levels of secretory IgA (s-IgA) and IL-1β in the saliva of smokers with dental caries, and to discover the correlation between these parameters and dental caries. Methods. Saliva samples were collected from 30 smokers, age range 21–70 years, with dental caries, in addition to 18 healthy non-smoker volunteers, age range 21–65 years. s-IgA and IL-1β levels in the saliva samples were estimated by enzyme-linked immunosorbent assay (ELISA). Results. The mean saliva IgA levels between smokers with dental caries group and healthy subjects were not significantly different (p=0.077), while the saliva levels of IL-1β were higher in the smokers in dental caries group, with a significant difference of p<0.05. No significant associations were found between s-IgA and IL-1β levels, and other parameters such as age, sex, body mass index (BMI) and C-reactive protein (CRP) (p>0.05). There were highly positive associations and significant differences between IL-1β and CRP levels in the two groups under the study (p=0.006). Conclusions. Our study revealed a significant increase in IL-1β levels in saliva of smokers with dental caries, and a positive association between IL-1β levels and caries disease. There is no significant relationship between elevated IL-1β levels and s-IgA in smokers with dental caries.

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“…Based on the description of the opinion above, it can be concluded that exercises is a process of improving the abilities of a person in a certain sport systematically and repeatedly by always providing exercises load in order to achieve the stated goals. The exercise was carried out for 8 consecutive times consisting of a 10-minute warm-up session and 45 minutes of technical exercises (Peres et al, 2019). The drill method is a way of teaching where students carry out exercises activities, so that students have dexterity or skills that are higher than what has been learned (Astuti, 2018).…”

Section: Introductionmentioning

confidence: 99%

The Effect of Exercise Variations in Improving Students’ Volleyball Forearm Pass Ability

Astuti¹,

Zulbahri²

2021

Advances in Social Science, Education and Humanities Research

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This research was conducted due to the students low ability in volleyball forearm pass technique at the Physical Education and Recreation Study Program. Therefore, many students had to repeat the test in the midterm and final semester exams. The research aims to determine the effect of exercise variations in improving the volleyball forearm pass ability by the students at the Physical Education and Recreation Study Program. Furthermore, an experiment with a one group pretest-postest design was used. The population consists of 150 students that participated in the volleyball courses in the semester from January -June 2020. The samples were taken using probability sampling techniques from 10% of the total population of 15 people. Data collection was carried a test of forearm pass skills, and the volleyball test from Brady. The data analysis technique was performed using the t-test over the assumed prerequisite test for data normality. The expected technological readiness in this study was TKT 3 using variation exercise methods to improve the students' skills in the forearm strike technique. The results showed that there was a significant influene between the exercise variations on the ability of the volleyball forearm pass technique with tcount = 8.52 = ttable = 2.14.

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Salivary levels of Interleukin-6 and Tumor Necrosis Factor-alpha in girls aged 7–17 years practicing volleyball

Cited by 6 publications

References 47 publications

Salivary levels of Interleukin-6, Interleukin-8 and Tumor Necrosis Factor-alpha in Smokers Aged 35-46 Years with Dental Caries Disease

Salivary levels of Interleukin-6, Interleukin-8 and Tumor Necrosis Factor-alpha in Smokers Aged 35-46 Years with Dental Caries Disease

Correlation between salivary immunoglobulin A and interleukin-1beta in smokers with dental caries

The Effect of Exercise Variations in Improving Students’ Volleyball Forearm Pass Ability

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