Salivary Protein Carbonyl Level in Relation to Gingival Health Status among a Group of Iraqi Pregnant Women

Abstract

Background:There is an increased oxidative stress during pregnancy that might affect their gingival health. This study was conducted to measure salivary protein carbonyl level of pregnant women and its relation with gingival health also compared the data obtained with those from healthy married non-pregnant women. Material and Methods: Thirty pregnant women during third trimester (i.e. study group) and thirty married non-pregnant women (i.e. control group) were selected from the Primary Health Care Centers in Baghdad city. The age range of both groups was 25-30 years. Stimulated saliva was collected and salivary protein carbonyl was analyzed using protein carbonyl assay kit. Plaque index (PlI) was used for measuring dental plaque thickness while gingival index (GI) was used for diagnosis of gingival disease. Results: The mean values of salivary protein carbonyl, plaque and gingival indices were highly significantly higher among pregnant than non-pregnant women (P˂0.01). Person's correlation coefficient showed positive strong highly significant correlation (P˂0.01) between plaque accumulation and gingivitis among pregnant and non-pregnant women. While non-significant correlations (P>0.05) were recorded between salivary protein carbonyl levels with both gingival and dental plaque indices among both pregnant and non-pregnant women. Conclusion: Although dental plaque is the main etiological factor in pregnancy gingivitis, protein oxidation represented by salivary protein carbonyl level could play a role in gingival inflammation during pregnancy. Therefore examining the proteomic profile along with protein oxidation is recommended that helps in early detection and monitoring of periodontal infection during pregnancy.

Assessment of Oral Hygiene and Gingival Health Condition and their Relationship with Some Salivary Variables among Boxers

“…Dental Plaque induced gingivitis may exhibit various patterns of observable signs and symptoms of inflammation localized to the gingiva and initiated by accumulating a microbial biofilm on teeth (5)(6). salivary components are important determinants of oral health status (7). Saliva consists of approximately 99.5% water for stimulated Saliva and 99.4% for unstimulated Saliva (8).…”

Salivary protein carbonyl and selected antioxidants in relation to dental caries among pregnant women

“…Also Elevated salivary protein carbonyl levels indicate higher salivary protein oxidation. was found among pregnant women (13). Wagle et al ( 14) recorded higher oxidative damage (Malondialdehyde "MDA" content) and low level of total anti-oxidant capacity in saliva during pregnancy.…”