Salix caprea inhibits skin carcinogenesis in murine skin: inhibition of oxidative stress, ornithine decarboxylase activity and DNA synthesis

Sultana, Sarwat; Saleem, Mohammmad

doi:10.1016/j.jep.2003.12.028

Cited by 27 publications

(18 citation statements)

References 47 publications

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“…Moreover, Salix species also have anti-oxidant (Alam et al, 2006), anti-inflammatory (Li et al, 2008), antiobesity (Han et al, 2003), and anti-tumor (Sultana et al, 2004) effects. Salix Koreensis Andersson in DC.…”

Section: Introductionmentioning

confidence: 99%

Anti-oxidant and anti-inflammatory effects of Salix Koreensis Andersson in DC. leaf methanol extract in vitro models

Kim¹,

Kim²

2016

TANG [HUMANITAS MEDICINE]

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Oxidative rancidity in foods causes undesirable changes in nutritive value, aroma, flavor, and color. Salix Koreensis Andersson in DC. (SK) has anti-oxidative and anti-inflammatory effects and is traditionally used to treat neuralgia, edema, pain, and inflammatory diseases. However, the regulatory effects of SK on oxidative and inflammatory reactions have not been elucidated. In this context, we scientifically validated the anti-oxidative and anti-inflammatory activities of SK leaf (SKL). The methanol extract of SKL was evaluated for in vitro anti-oxidative activities. SKL showed increased superoxide dismutase (SOD)-like activity and 1, 1-diphenyl-2-picrylhydrazyl radical scavenging activity. The in vitro anti-oxidant and antiinflammatory activities of SKL were also investigated in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages. LPS resulted in decreased SOD activities compared with the unstimulated cells, but SKL significantly increased SOD activities reduced by LPS. In addition, LPS-induced nitric oxide, tumor necrosis factor-α, and interleukin-6 productions were significantly and dose-dependently reduced by SKL in RAW264.7 macrophages without inducing cytotoxicity. In conclusion, these results indicate that SKL will be able to be effectively used as a food additive with anti-oxidative and anti-inflammatory effects.

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Section: Introductionmentioning

confidence: 99%

Anti-oxidant and anti-inflammatory effects of Salix Koreensis Andersson in DC. leaf methanol extract in vitro models

Kim¹,

Kim²

2016

TANG [HUMANITAS MEDICINE]

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“…It is recognized as an inflammatory agent [2] and tumor promoter that has been shown to generate superoxide anion, hydrogen peroxide, and lipid hydroperoxides, leading to oxidative stress. Topical application of TPA on mouse skin resulted in discernible oxidative response as measured by increased hydrogen peroxide and MDA production and depletion of antioxidant defense like catalase [8] and GSH.…”

Section: Resultsmentioning

confidence: 99%

“…The generation of reactive oxygen species (ROS) and their subsequent accumulation induces oxidative stress at the cellular level [2]. Although almost all organisms possess antioxidant defense and repair systems that have evolved to protect them against oxidative damage, these systems are insufficient to prevent the damage entirely.…”

Section: Introductionmentioning

confidence: 99%

Protective Effect of Fermented Soybean Dried Extracts against TPA-Induced Oxidative Stress in Hairless Mice Skin

Georgetti

Casagrande

Vicentini

et al. 2013

BioMed Research International

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This study evaluated the chemical properties (polyphenol and genistein contents) of soybean extracts obtained by biotransformation and dried by spray dryer at different conditions and their in vivo ability to inhibit 12-O-tetradecanoylphorbol-13-acetate- (TPA-) induced biochemical alterations in the skin of hairless mice. By comparing the obtained data with that of the well-known active soybean extract Isoflavin beta, we evaluated the influence of the fermentation and drying process in the extracts efficacy. The results demonstrated that inlet gas temperature and adjuvant concentration for the extract drying process have significantly affected the total polyphenol contents and, to a minor degree, the genistein contents. However, the effect of topical stimulus with TPA, an oxidative stress inducer, which caused significant depletion of reduced glutathione (GSH) and catalase, with increased levels of H2O2 and lipid peroxidation (MDA) in the skin of hairless mice, was significantly prevented by the soybean extracts treatment. These results indicate that the spray drying processing resulted in a product capable of limiting the oxidative stress with possible therapeutic applicability as an antioxidant in pharmaceutical forms.

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“…12-O-tetradecanoyl-13-phorbol acetate isolated (TPA) (Sultana et al, 2004). Salix caprea stemwood and knots were found to contain the phenolic compounds, viz., vanillic acid, 3-p-coutharyl alcohol, coniferyl alcohol, sinapylaldehyde, dihydrokaemerol, catechin, naringenin, gallocatechin, dihydromyrcetin and taxifolin (Pohjamo et al, 2003).…”

Section: Use In Tsmmentioning

confidence: 99%

“…The floral scent compound (1, 4-dimethoxybenzene) of the plant has shown attracting effect of an oligolectic bee (Dotterl et al, 2005). The plant inhibits skin carcinogenesis in marine skin, inhibition of oxidative stress, ornithine decarboxylase activity in DNA synthesis (Sultana et al, 2004).…”

Section: Bioactivitymentioning

confidence: 99%

An overview and economical importance of few selected endangered medicinal plants grown in Jammu and Kashmir region of India

Rasool¹,

Khan²,

Hamid³

et al. 2016

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Medicinal plants as a group comprise approximately 8000 species and account for around 50% of all the higher flowering plant species of India. Millions of rural households use medicinal plants in a self-help mode. Over one and a half million practitioners of the Indian System of Medicine in the oral and codified streams use medicinal plants in preventive, promotive and curative applications. In recent years, the growing demand for herbal product has led to a quantum jump in volume of plant materials traded within and across the countries. Further, in view of the side effects of synthetic drugs coupled with their high cost of production, medicinal plants have become major sectors of trade and commerce and are significantly contributing to the socioeconomic developments of certain developed and developing countries. Though India has a rich biodiversity, the growing demand is putting a heavy strain on the existing resources. Among various States of India, Jammu and Kashmir State has a rich diversity of medicinal plants because it provides a diverse type of habitats for their growth. Kashmir valley represents the temperate region, Jammu area represents sub-tropical and tropical and Ladakh as cold desert region. More than 50% of plant based medicines prescribed in British Pharmacopoeia are growing in Jammu and Kashmir State.In the present paper, 13 important medicinal plants, viz., Achillea millefolium L., Aconitum heterophyllum Wall.ex Royle, Artemisia absinthium L., Asplenuim adiantum-nigrum L., Berberis lycium Royle, Cydonia oblonga Miller, Delphinium denudatum Wall.ex.H&T, Picrorhiza kurroa Royle.ex.Benth, Po dop hyllum hex and rum Royle, Prune lla vu lga ris L., Sa lix cap rea L., Taraxacum officinale Webber. and Viola odorata L. with attributes to traditional system of medicine and their use by local population in primary health care have been described. The vernacular names, distribution pattern, folk use, use in traditional system of medicine (TSM), phytochemical constituents isolated and characterized in each plant species are discussed. The present status, in State of nature of each plant species based on ethnobotanical exploration made by authors from time to time and future prospects for commericial cultivation is discussed.

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Salix caprea inhibits skin carcinogenesis in murine skin: inhibition of oxidative stress, ornithine decarboxylase activity and DNA synthesis

Cited by 27 publications

References 47 publications

Anti-oxidant and anti-inflammatory effects of Salix Koreensis Andersson in DC. leaf methanol extract in vitro models

Anti-oxidant and anti-inflammatory effects of Salix Koreensis Andersson in DC. leaf methanol extract in vitro models

Protective Effect of Fermented Soybean Dried Extracts against TPA-Induced Oxidative Stress in Hairless Mice Skin

An overview and economical importance of few selected endangered medicinal plants grown in Jammu and Kashmir region of India

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