Salmonella spondylodiscitis of the thoracic vertebrae mimicking spine tuberculosis

Effendi, F Muhamad; Ibrahim, Mohd Ikraam; Miswan, Mohd Fairudz Mohd

doi:10.1136/bcr-2016-215909

Cited by 7 publications

(5 citation statements)

References 9 publications

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“…Initially, we reviewed all cases of Salmonella-associated spondylitis reported in English with full texts available on PubMed and the Central Journal of Medicine, limited to adults 19 years and above. This search yielded 30 cases [ 5 - 34 ], 21 of which were identified as nontyphoidal Salmonella [ 5 - 25 ]. Of these, 17/21 (81.0%) patients reported local pain, and only 4/21 (19.0%) had no local pain (one case presented with impaired consciousness, one with spinal cord/peripheral nerve palsy, one with no clear identified cause, and one had no description provided).…”

Section: Discussionmentioning

confidence: 99%

An Atypical Case of Spondylitis Due to Nontyphoidal Salmonella in an Adult Patient: A Case Report and Review of the Literature

Hamada,

Furukawa,

Kikuchi

et al. 2024

Cureus

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Nontyphoidal Salmonella commonly induces intestinal infections; however, spondylitis arising from this bacterium is exceedingly rare. A comprehensive review of the clinical attributes of nontyphoidal Salmonella-induced spondylitis in adult populations is lacking in the literature. We report a case of an 83-year-old female who presented with a fever lasting three days, accompanied by anorexia and pervasive malaise. A month prior, she had been prescribed celecoxib and had received a trigger point injection. The patient was initially diagnosed with acute pyelonephritis and treated with an antimicrobial regimen. However, a week later, although her fever persisted, there was no complaint of back pain. The discontinuation of celecoxib led to back pain. Subsequent urine and blood cultures, coupled with MRI findings, confirmed the diagnosis of pyogenic spondylitis attributable to the Salmonella O7 group. The patient’s fever abated with the administration of antimicrobial agents, and her back pain subsided. The antimicrobial regimen was continued for 12 weeks, with no resurgence of fever or back pain following treatment. Local pain and fever are important indicators for the diagnosis of spondylitis caused by nontyphoidal Salmonella. It is critical to take an accurate history of non-steroidal anti-inflammatory drugs (NSAIDs) use, such as celecoxib, since NSAIDs can obscure the symptoms. Blood cultures are equally important, given their propensity to yield positive results in these patients.

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Section: Discussionmentioning

confidence: 99%

An Atypical Case of Spondylitis Due to Nontyphoidal Salmonella in an Adult Patient: A Case Report and Review of the Literature

Hamada,

Furukawa,

Kikuchi

et al. 2024

Cureus

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“…Salmonella and Mycobacterium infections occur in endemic regions. Both infections are characterized by the invasion of the bony spine, paravertebral tissue, spondylodiscitis, and psoas muscle abscesses (14,15). When investigating the potential source of infection, we discovered that the patient resided in an environment where cattle farming was commonplace; he consumed homemade air-dried raw beef and unpasteurized milk.…”

Section: Discussionmentioning

confidence: 99%

Case report: Uncommon presentation of Salmonella Dublin infection as a large paravertebral abscess

An,

Wu,

Zhong

et al. 2023

Front. Med.

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BackgroundSalmonella Dublin is a zoonotic pathogen that is associated with invasive infections and high morbidity and mortality rates. Here we present the case of a 78-year-old man with a rare manifestation of a paravertebral abscess in the thoracolumbar spine caused by Salmonella Dublin.Case presentationThe patient had a history of spinal tuberculosis and poorly controlled diabetes. The abscess was successfully managed by drainage, and a 12-week course of moxifloxacin resulted in complete recovery. Salmonella Dublin was identified using culture-based serotyping. The patient resided in an environment where cattle farming is common; he consumed raw beef and unpasteurized milk, suggesting a potential source of infection.DiscussionIncreasing the awareness of Salmonella Dublin as a potential cause of spinal abscesses is important, particularly in patients with structural spinal abnormalities. The timely initiation of appropriate antimicrobial therapy based on susceptibility testing is recommended. This case highlights the pathogenic potential of Salmonella Dublin and emphasizes the importance of effectively managing invasive Salmonella infections.

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“…Pyogenic spondylodiscitis caused by Salmonella species is rare, as the organism usually manifests infection in the intestinal tract. There were two reported cases of Salmonella spondylodiscitis in Malaysia, and both were successfully treated with a course of antibiotics [1,2]. Mazlan et al reported that their patient was successfully treated with intravenous ampicillin 2 g for two weeks, followed by oral ciprofloxacin 750 mg for three months [1].…”

Section: Introductionmentioning

confidence: 99%

“…There were two reported cases of Salmonella spondylodiscitis in Malaysia, and both were successfully treated with a course of antibiotics [1,2]. Mazlan et al reported that their patient was successfully treated with intravenous ampicillin 2 g for two weeks, followed by oral ciprofloxacin 750 mg for three months [1]. Another case reported the use of ceftriaxone for two months in the treatment of Salmonella spondylodiscitis patient [2].…”

Section: Introductionmentioning

confidence: 99%

“…Mazlan et al reported that their patient was successfully treated with intravenous ampicillin 2 g for two weeks, followed by oral ciprofloxacin 750 mg for three months [ 1 ]. Another case reported the use of ceftriaxone for two months in the treatment of Salmonella spondylodiscitis patient [ 2 ]. We report a case of Salmonella enteritidis spondylodiscitis that shows no clinical improvement after a course of antibiotics.…”

Section: Introductionmentioning

confidence: 99%

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Single-Stage Debridement and Spinal Instrumentation for Salmonella Spondylodiscitis of Thoracic Vertebra

Zaki¹,

Ariffin²

2021

Cureus

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For patients with pyogenic spondylodiscitis, medical therapy with antibiotics is the first line of treatment. Response to antibiotics can be assessed by improvement of symptoms, reduction in inflammatory markers, and radiological evidence of infection resolution with magnetic resonance imaging (MRI). We report a case of a 60-year-old man who presented with intermittent fever and persistent back pain. He was initially treated with an intravenous antibiotic for sepsis secondary to Salmonella enteritidis bacteremia. His spine MRI showed compression of the T10 vertebra with vertebral abnormality suggestive of metastases. He showed no clinical improvement after a course of intravenous antibiotics. Following that, debridement and spinal instrumentation of the thoracic vertebra were done in single-stage surgery.

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Salmonella spondylodiscitis of the thoracic vertebrae mimicking spine tuberculosis

Cited by 7 publications

References 9 publications

An Atypical Case of Spondylitis Due to Nontyphoidal Salmonella in an Adult Patient: A Case Report and Review of the Literature

An Atypical Case of Spondylitis Due to Nontyphoidal Salmonella in an Adult Patient: A Case Report and Review of the Literature

Case report: Uncommon presentation of Salmonella Dublin infection as a large paravertebral abscess

Single-Stage Debridement and Spinal Instrumentation for Salmonella Spondylodiscitis of Thoracic Vertebra

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