Salmonella typhi endocarditis: a case report

Khan, Ghulam Qadir; Kadri, SM; Hassan, Ghulam; Shahid, Izza; Gazanfar, A; Kak, M; Showkat, Hakim İrfan

doi:10.1136/jcp.56.10.801

Cited by 23 publications

(9 citation statements)

References 2 publications

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“…Staphylococcus aureus and NTS are two of the most common pathogens isolated from mycotic aortic aneurysms [ 9 ]. NTS has also been documented to cause other cardiac complications, such as myocarditis, pericarditis, and endocarditis [ 10 ]. In our patient’s case, it is likely that he developed a gastrointestinal infection with NTS with subsequent distant seeding.…”

Section: Discussionmentioning

confidence: 99%

Nontyphoidal Salmonella as a Cause of Mediastinal Abscess in a Patient With Extensive Cardiac Surgery

Dohogne¹,

Srinivasan²,

Arif-Tiwari³

et al. 2020

Cureus

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Focal infections caused by nontyphoidal Salmonella (NTS) are relatively rare and usually self-limited. Those with cardiac surgical history are predisposed to intrathoracic seeding, including mediastinal infections and abscesses. We report a case of a 39-year-old Hispanic male with a complex past medical history of Tetralogy of Fallot with an initial presentation of Salmonella gastroenteritis and concern for sepsis. The patient did not clinically improve on ceftriaxone despite appropriate cultures and susceptibilities, and another source of infection was speculated. A chest CT scan showed development of a mediastinal abscess with compression of the right ventricular outflow tract. The patient was not deemed an appropriate surgical candidate and was managed conservatively on ceftriaxone and ciprofloxacin. He was discharged in stable condition. This case of NTS infection associated with a mediastinal abscess is a rare occurrence, and management is complicated. To improve morbidity and mortality, early imaging is essential to diagnose distal seeding of the infection in patients with enteral infections who do not show clinical improvement despite appropriate antibiotic treatment. Surgery is the standard of care, but conservative management might be required in certain high-risk cases.

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Section: Discussionmentioning

confidence: 99%

Nontyphoidal Salmonella as a Cause of Mediastinal Abscess in a Patient With Extensive Cardiac Surgery

Dohogne¹,

Srinivasan²,

Arif-Tiwari³

et al. 2020

Cureus

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“…Because the causative agent of typhoid fever can, in rare cases, cause infective endocarditis, the presence of uncommon etiologies should be considered for febrile cases with symptoms suggestive of endocarditis. 36 This study provides a snapshot of communicable disease frequency at the selected hospitals from 2008 to 2011 in Georgia. On the basis of these results, one could speculate that, with the exception of WNV, the targeted pathogens are prevalent among febrile patients in the country (to varying degrees).…”

Section: Discussionmentioning

confidence: 99%

Hospital-Based Surveillance for Infectious Etiologies Among Patients with Acute Febrile Illness in Georgia, 2008–2011

Kuchuloria¹,

Imnadze²,

Mamuchishvili³

et al. 2016

The American Society of Tropical Medicine and Hygiene

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Abstract. Information on the infectious causes of undifferentiated acute febrile illness (AFI) in Georgia is essential for effective treatment and prevention. In May 2008, a hospital-based AFI surveillance was initiated at six hospitals in Georgia. Patients aged ≥ 4 years with fever ≥ 38°C for ≥ 48 hours were eligible for surveillance. Blood culture and serologic testing were conducted for Leptospira spp., Brucella spp., West Nile virus (WNV), Crimean-Congo hemorrhagic fever virus, Coxiella burnetii, tick-borne encephalitis virus (TBEV), hantavirus, Salmonella enterica serovar Typhi (S. Typhi), and Rickettsia typhi. Of 537 subjects enrolled, 70% were outpatients, 54% were males, and the mean age was 37 years. Patients reported having fatigue (89%), rigors (87%), sweating (83%), pain in joints (49%), and sleep disturbances (42%). Thirty-nine (7%) patients were seropositive for R. typhi, 37 (7%) for Brucella spp., 36 (7%) for TBEV, 12 (2%) for Leptospira spp., 10 (2%) for C. burnetii, and three (0.6%) for S. Typhi. None of the febrile patients tested positive for WNV antibodies. Of the patients, 73% were negative for all pathogens. Our results indicate that most of the targeted pathogens are present in Georgia, and highlight the importance of enhancing laboratory capacity for these infectious diseases.

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“…Salmonella endocarditis is characterized by a destructive process, characterized by valve perforation, valve ring abscess, atrio-ventricular wall perforation, and/or valvular cusp rupture [ 320 ]. Other frequent complications include atrial thrombus formation / mural endocarditis, myocarditis, and pericarditis [ 324 ]. As a result of this destructive capacity, previously reported mortality rates are ~70 % [ 325 ].…”

Section: Gram-negative Bacillimentioning

confidence: 99%

Endocarditis

2016

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Salmonella typhi endocarditis: a case report

Cited by 23 publications

References 2 publications

Nontyphoidal Salmonella as a Cause of Mediastinal Abscess in a Patient With Extensive Cardiac Surgery

Nontyphoidal Salmonella as a Cause of Mediastinal Abscess in a Patient With Extensive Cardiac Surgery

Hospital-Based Surveillance for Infectious Etiologies Among Patients with Acute Febrile Illness in Georgia, 2008–2011

Endocarditis

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