Salmonella typhi Meningitis

Abstract

Whereas typhoid fever is still an endemic disease in some parts of the world, meningeal involvement in this disease is a rare occurrence. We report a case of Salmonella typhi meningitis in a 70-year-old woman. The patient was treated with ampicillin and the only sequela was right-sided deafness.

Salmonella Meningitis in an Immunocompetent Adult

“…Our review of the English language medical literature reveals a number of case series and case reports of salmonella meningitis, totaling approximately 40 adult, probably immunocompetent patients, many of whom had risk factors for developing non-enteric salmonella infection (13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23). In 1979, Kauffmann and St. Hilaire reviewed the existing literature in their case report of a man who developed salmonella meningitis after steroid treatment for a lumbar spine fracture complicated by paraplegia.…”

Salmonella meningitis and septicaemia in an non-immunocompromised adult, associated with a cluster of Salmonella Enteritidis PT 14b, Ireland, November 2009

“…However, the European literature includes only two previous case reports of adults with meningitis due to Salmonella Enteritidis, one of whom was immunocompromised [15,16]. Other cases of Salmonella meningitis in adults previously reported in the literature have involved a diversity of serotypes, including at least 19 cases of S. Typhi [17][18][19][20][21][22], two cases of S. Typhimurium [18,11], and one case each of S. Oranienburg [23], S. Virchow [24], S. Paratyphi [21] and S. Berta [25].…”

Salmonella Meningitis: Report of Three Cases in Adults and Literature Review

“…Salmonella meningitis in association with enterovirus as well as following instances of meningococcal meningitis have been described [6,23]. Reported CSF findings in both adults and children with S. typhi meningitis vary from predominantly lymphocytic to neutrophilic and from a minimal pleocytosis to frankly purulent, perhaps a reflection of time to presentation or prior use of antibiotics [24][25][26].…”