BackgroundType 2 diabetes (T2D) is one of public health concerns in China with a rapid increase in prevalence. The study on salt intake and risk of T2D is still lack in China.AimsTo investigate the association between dietary salt intake levels and the glycaemia response of T2D.MethodsA total of 1145 T2D patients, who accepted standardized management by the National Standardized Metabolic Disease Management Center at Ningbo First Hospital from March 2018 to January 2020, were selected in the final analysis. Demography, lifestyle and medical information were collected through questionnaires. Anthropometry, blood pressure and biomarkers were measured by well-trained endocrinology nurses. Generalized linear models (GLM) were used to examine the association.ResultsHigher prevalence of overweight and central obesity with larger BMI and waist circumference were found in higher salt categories 6-8g/d and ≥8g/d, compared to lower salt categories. Fasting plasma glucose (FPG), 2h postprandial plasma glucose, 2h postprandial insulin, total cholesterol, triglyceride and low-density lipoprotein cholesterol were significantly different across salt intake categories. GLM further shows that salt intake 6-8g/d and ≥8g/d were positively associated with FPG and salt intake 6-8g/d and ≥8g/ d was associated with HbA1c.ConclusionIncreasing salt intake is suggested to be associated with the glycaemia response at the fasting state in T2D patients. Hospital-based education is needed for improvement of awareness, attitude and action on restriction of salt consumption.