2012
DOI: 10.5646/jksh.2012.18.2.53
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Salt, Hypertension, and Cardiovascular Diseases

Abstract: ❙ABSTRACT❙The relationship between salt and hypertension is well established, and salt restriction is widely recommended in the management of hypertension. However, people living in northeast Asia have consumed large amount of salt, and the prevalence of hypertension and the incidence of stroke have been high in that area. Mechanisms of salt-induced hypertension may be complex, but volume expansion in the presence of impaired natriuretic capacity of the kidney and action on the central nervous system and neuro… Show more

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Cited by 5 publications
(2 citation statements)
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“…No correlation between BP and sodium excretion was observed in the current study, and this was inconsistent with a number of previous studies showing strong correlations between excessive salt intake and increases in BP, and the progression of hypertension [6]. Our study may have been under-powered (small sample size), and the study exclusion criteria may also have contributed to this unexpected finding.…”
Section: Discussioncontrasting
confidence: 99%
See 1 more Smart Citation
“…No correlation between BP and sodium excretion was observed in the current study, and this was inconsistent with a number of previous studies showing strong correlations between excessive salt intake and increases in BP, and the progression of hypertension [6]. Our study may have been under-powered (small sample size), and the study exclusion criteria may also have contributed to this unexpected finding.…”
Section: Discussioncontrasting
confidence: 99%
“…Thus, high sodium intake increases the risk of cardiovascular disease and mortality [6,7], and may as well have other harmful effects including increased risk of stroke, heart failure, osteoporosis, obesity, gastric cancer, and chronic kidney disease [8]. Therefore, the WHO has acknowledged high sodium intake as one of the silent killers of humans responsible for roughly 2.3 million deaths (4% of global mortality) in 2010 [1].…”
Section: Introductionmentioning
confidence: 99%