2020
DOI: 10.1016/j.jacc.2019.11.055
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Salt Reduction to Prevent Hypertension and Cardiovascular Disease

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Cited by 388 publications
(319 citation statements)
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“…In a recent review by He et al, the authors highlighted the diverse mechanisms whereby a high dietary salt intake may contribute to a greater risk of CVD [ 10 ]. Eminently, of the 10 million CVD-related deaths attributed to dietary risk factors in 2017, a high dietary salt intake was the leading risk factor [ 9 ].…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…In a recent review by He et al, the authors highlighted the diverse mechanisms whereby a high dietary salt intake may contribute to a greater risk of CVD [ 10 ]. Eminently, of the 10 million CVD-related deaths attributed to dietary risk factors in 2017, a high dietary salt intake was the leading risk factor [ 9 ].…”
Section: Discussionmentioning
confidence: 99%
“…Obese individuals are also more likely to have poor dietary habits, such as higher caloric intake accompanied by excessive salt intake, which is the leading dietary risk factors associated with cardiovascular and all-cause mortality [ 9 ]. While the adverse effects of excess salt intake on the cardiovascular system is well known [ 10 ], more attention has been brought to the role of cardiotonic steroids, which are associated with increased salt intake in the development of CVD. This includes the biomarker marinobufagenin (MBG) [ 11 ], which is synthesized and secreted by the adrenal cortex in response to sodium loading [ 12 ].…”
Section: Introductionmentioning
confidence: 99%
“…Gustatory threshold for salty taste (mg/cm 2 Continuous variables are presented as mean ± standard deviation. Categorical variables are presented as percentages or numbers.…”
Section: On Admission 3 Months After Admission P-valuementioning
confidence: 99%
“…Gustatory threshold for salty taste (mg/cm 2 Propensity score matching was performed, and 105 patients were extracted from each group. Score-matched patients' backgrounds are shown in the Supplemental Material (Table S2).…”
Section: On Admission 3 Months After Admission P-valuementioning
confidence: 99%
“…High sodium consumption causes various lifestyle-related diseases such as hypertension, cardiovascular disease, kidney disease, stomach cancer, and osteoporosis, both directly and indirectly (He, Tan, Ma, & MacGregor, 2020;Malta et al, 2018). The World Health Organization (WHO) has strongly recommended an average salt intake of <5 g/day for the general adult populations of all countries (WHO, 2003) and has set a global target of reducing salt intake by a relative 30% by 2025 (WHO, 2012).…”
Section: Introductionmentioning
confidence: 99%