Salvadora persica: Nature’s Gift for Periodontal Health

Abstract

Salvadora persica (SP) extract, displays very valuable biotherapeutic capacities such as antimicrobial, antioxidant, antiparasitic and anti-inflammatory effects. Numerous investigations have studied the pharmacologic actions of SP in oral disease therapies but its promising outcomes in periodontal health and treatment are not yet entirely described. The current study has been planned to analyze the reported effects of SP as a support to periodontal therapy to indorse regeneration and healing. In consort with clinical trials, in vitro investigations show the advantageous outcomes of SP adjunctive to periodontal treatment. Yet, comprehensive supplementary preclinical and clinical investigations at molecular and cellular levels are indispensable to reveal the exact therapeutic mechanisms of SP and its elements for periodontal health and therapy.

HPLC/MSn Profiling and Healing Activity of a Muco-Adhesive Formula of Salvadora persica against Acetic Acid-Induced Oral Ulcer in Rats

“…For this reason, natural products have attracted great attention, as they constituted 16% of FDA-approved drugs in 2018 [ 44 ]. In particular, S. persica is considered to be nature’s gift for oral health [ 45 , 46 ]. The current study presents a phytochemical profile of SPEAF using HPLC-ESI-QTOF-MS-MS analysis.…”

Antidepressant‐like effects of aqueous extracts of miswak ( Salvadora persica ) and date palm ( Phoenix dactylifera ) on depression‐like behaviors using CUMS model in male rats

“…It is commonly used as a tooth‐cleaning stick in many African and Middle Eastern countries (Aumeeruddy et al, 2018). It contains salvadorine and trimethylamine as major constituents besides other flavonoids and alkaloids, which show antiseptic properties and other effects such as antiemetic, antiallergic, antitussive, antioxidant, anti‐inflammatory activities, and antiprotozoal (Saeedi Borujeni et al, 2019; El‐Bali et al, 2020; Mekhemar et al, 2021).…”

Evaluation of Nutritional, Phytochemical, and Mineral Composition of Selected Medicinal Plants for Therapeutic Uses from Cold Desert of Western Himalaya

“…The analgesic activity, antibacterial activity, anticataleptic activity, antidiabetic and antihyperlipidemic activity, antifungal activity, antihypercholesterolemic activity, antimicrobial activity, antioxidant activity, diuretic, anti-inflammatory properties, hepatoprotective activity, and neuroprotective activity in Parkinson’s disease are all properties of Ginsenosides plants (Pinales). The determination of physiochemical and biological characteristics, sensory evaluation, and chemical composition analysis are all part of the entire characterization of an essential oil [ 7 , 8 ].…”