“…Additionally, HD may cause QOL impairments [1,2,16,17]. The ESRD patients, regardless of the treatment modality, have to manage many adversities: cognitive impairment, physical symptoms, fluid and dietary restriction, and changed body image [3,5,6,15,18,19]. They may have many risk factors of reduced QOL such as diabetes, hypertension, dyslipidemia, hypoxemia, proinflammatory state, as well as fluid, osmolar and uremic toxin variations [6].…”