Same-eye comparison of pupillary dilation with an intraoperative standardized intracameral combination of mydriatics (Mydrane®) versus a preoperative ophthalmic (Mydriasert®) in standard cataract surgery in non-diabetic patients

Faria, A. De; Giorgi, Roch; Salmon, Mike; Bonnel, S.; Holweck, G.; Corre, A. Le; Chazalon, E.

doi:10.1016/j.jfo.2019.07.001

Cited by 4 publications

(8 citation statements)

References 17 publications

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“…This finding is in line with the results of previous studies, along with the finding that surgeon satisfaction with mydriasis was lower in the ICMA group. 5,[16][17][18][19][20] Despite the lower pupil diameter in the ICMA group, there was no statistically significant difference between groups in the number of patients who required additional intraoperative mydriatics. By contrast, a previous study found that 1.1% of patients receiving ICMA and 5.3% of patients receiving topical mydriatics required additional intraoperative mydriatics before successful capsulorhexis could be achieved.…”

Section: Discussionmentioning

confidence: 99%

Cost analysis of mydriasis strategies in cataract surgery care in the Netherlands

Simons

Rondas

Biggelaar

et al. 2021

J Cataract Refract Surg

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Section: Discussionmentioning

confidence: 99%

Cost analysis of mydriasis strategies in cataract surgery care in the Netherlands

Simons

Rondas

Biggelaar

et al. 2021

J Cataract Refract Surg

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“…Notably, a 0.2-mL dose contains 0.62 mg of phenylephrine, 0.04 mg of tropicamide, and 2 mg of lidocaine hydrochloride. 13,14 Our findings suggest that topical anesthesia plus intracameral anesthesia results in a lower pain score than topical anesthesia alone during the procedure and over 24 hours postoperatively. (p = 0.02 and p = 0.01, respectively).…”

Section: Discussionmentioning

confidence: 80%

“…Notably, a 0.2-mL dose contains 0.62 mg of phenylephrine, 0.04 mg of tropicamide, and 2 mg of lidocaine hydrochloride. 13,14…”

Section: Discussionmentioning

confidence: 99%

Pain experience in patients undergoing topical anesthesia alone versus topical plus intracameral anesthesia during cataract surgery

Ripa

Ricci

Rizzo

2023

European Journal of Ophthalmology

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Purpose To evaluate and compare the pain experience and discomfort during cataract surgery and over the 24 hours after surgery in patients undergoing either topical anesthesia alone or topical anesthesia plus intracameral anesthesia, provided by using a standard topical anesthesia regimen and a 0.2-mL dose of Mydrane®. Methods Prospective study involving 100 patients who underwent cataract surgery receiving either topical anesthesia alone (group 1, n = 50) or topical anesthesia plus intracameral anesthesia (group 2, n = 50) between January 2021 and March 2022. The pain experienced by patients during and after surgery was assessed using a pain scale and a questionnaire. One hour after surgery, patients were asked to rate the intensity of discomfort they experienced throughout the procedure by pointing to a 0–100 Visual Analogue Scale (VAS). Results According to VAS measurements, patients who underwent surgery under topical anesthesia reported more significant pain than those who underwent surgery under topical anesthesia plus intracameral anesthesia during and over the 24 hours after surgery. ( p = 0.02 and p = 0.01, respectively). Patients undergoing topical anesthesia had 2.34-fold greater odds of having pain during surgery [95% Confidence Interval (CI): 1.58–5.25, p = 0.03]. Conclusions Topical anesthesia plus intracameral anesthesia lower intraoperative and postoperative pain levels, improving patient cooperation and representing a useful analgesic delivery method in cataract surgery.

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“…In 2015, a standardized combination of mydriatics (0.02% tropicamide, 0.31% phenylephrine) and an anesthetic (1% lidocaine) [25] (SCIMA)-Mydrane-was introduced in the form of intracameral injections to obtain mydriasis during cataract surgery. One 0.2 mL dose contains 0.04 mg of tropicamide, 0.62 mg of phenylephrine hydrochloride, and 2 mg of lidocaine hydrochloride [11,26]. The mydriatic effect of those combined substances in one solution is greater than that of any of these agents alone [27].…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of a Standardized Combination of Intracameral Mydriatics and Anaesthetic on Mydriasis during Cataract Surgery with Coexisting Diseases

Dereń-Szumełda,

Dorecka,

Zandecki

et al. 2023

Life

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Purpose: To examine the effectiveness of a standardized combination of intracameral mydriatics and anesthetic (SCIMA) on mydriasis in patients with coexisting diseases such as diabetes mellitus (DM) and pseudoexfoliation syndrome (PXF) during phacoemulsification. Methods: Patients with cataract were included in the study if they achieved pupil dilation diameter ≥ 6.0 mm after the administration of mydriatic eyedrops (ME) during the first visit (V1). During the second visit (V2), pupil size measurements were obtained for phacoemulsification surgery with SCIMA. Effective mydriasis was defined as a pupil diameter ≥ 6.0 mm just prior to capsulorhexis without the use of additional pupil dilating agents. The measurements after ME administration during V1 and after SCIMA use during V2 were compared. Results: 103 patients (103 eyes) were divided into 3 groups: cataract and DM (n = 35), cataract and PXF (n = 32), and cataract without DM or PXF (n = 36). SCIMA administration allowed the achievement of effective mydriasis (≥6.0 mm) in all groups (n = 103; 100%). Mydriasis was significantly larger (p ≤ 0.001) after ME (7.3 mm) than after SCIMA (6.8 mm) administration. Conclusions: Patients with cataract and such comorbidities as DM or PXF are likely to achieve effective pharmacological mydriasis during cataract phacoemulsification after SCIMA application. Mydriasis after ME is slower and larger, while SCIMA is faster.

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Same-eye comparison of pupillary dilation with an intraoperative standardized intracameral combination of mydriatics (Mydrane®) versus a preoperative ophthalmic (Mydriasert®) in standard cataract surgery in non-diabetic patients

Cited by 4 publications

References 17 publications

Cost analysis of mydriasis strategies in cataract surgery care in the Netherlands

Cost analysis of mydriasis strategies in cataract surgery care in the Netherlands

Pain experience in patients undergoing topical anesthesia alone versus topical plus intracameral anesthesia during cataract surgery

Effectiveness of a Standardized Combination of Intracameral Mydriatics and Anaesthetic on Mydriasis during Cataract Surgery with Coexisting Diseases

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