2018
DOI: 10.4049/jimmunol.200.supp.174.37
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Sample sparing platform for microscopy shows that CD45RB ligation increases Treg sensitivity to activation signals in vitro

Abstract: Small subpopulations of cells, e.g. regulatory T cells, often play key roles in the function of the entire immune system. While their smaller number makes them difficult to work with in conventional immunocytochemistry assays or flow cytometry, microscopy can provide functional and spatial information on a single cell basis. Combined with surface modification technology such as synthetic lipid bilayers and micropatterned antibodies, we are in a unique position to be able to study the spatial mobility of intrac… Show more

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