Sand production poses a significant problem for marine natural gas hydrate efficient production. However, the bottom hole gas–water–sand inflow pattern remains unclear, hindering the design of standalone screen and gravel packing sand control completions. Therefore, gas–water–sand inflow patterns were studied in horizontal and vertical wells with the two completions. The experimental results showed that gas–water stratification occurred in horizontal and vertical standalone screen wells. The gas–water interface changed dynamically, leading to an uneven screen plugging, with severe plugging at the bottom and high permeability at the top. The high sand production rate and low well deviation angle exacerbated screen plugging, resulting in a faster rising rate of the gas–water interface. The screen plugging degree initially decreased and then increased as the gas–water ratio increased, resulting in the corresponding variation in the gas–water interface rising rate. Conversely, gas–water stratification did not occur in the gravel packing well because of the pore throat formed between the packing gravels. However, the impact of gas and water led to gravel rearrangement and the formation of erosion holes, causing sand control failure. A higher gas–water ratio and lower packing degree could result in more severe destabilization. Therefore, for the standalone screen completion, sand control accuracy should be designed at different levels according to the uneven plugging degree of the screen. For the gravel packing completion, increase the gravel density without destabilizing the hydrate reservoir, and use the coated gravel with a cementing effect to improve the gravel layer stability. In addition, the screen sand control accuracy inside the gravel packing layer should be designed according to the sand size to keep long-term stable hydrate production.