Saponins Versus Plant Fungal Pathogens

Abdelrahman, Mostafa; Jogaiah, Sudisha

doi:10.1007/978-3-030-61149-1_4

Cited by 4 publications

(7 citation statements)

References 28 publications

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“…Cultivated vegetables, fruits, nuts, herbs, and spices have been investigated more thoroughly than wild species; thus, they dominate the list (Table 1). Although more than 7000 species of wild edible plants are present in human nutrition [20], their antimicrobial properties are poorly investigated, and most of them still need to be studied [21,22].…”

Section: Antimicrobial Properties Of Edible Plantsmentioning

confidence: 99%

“…There are three classes of saponins (triterpenoids, steroids and glycoalkaloids) based on their different aglycone structures [22]. The triterpenoid 18-β-glycyrrhetinic acid showed an antibiotic effect on Staphylococcus aureus by influencing some of its important genes [22]. In addition, this compound is an immunological adjuvant [80,81].…”

Section: Antimicrobial Properties Of Edible Plantsmentioning

confidence: 99%

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Antimicrobial Effect of Phytochemicals from Edible Plants

Hochma

Yarmolinsky²,

Khalfin

et al. 2021

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Current strategies of combating bacterial infections are limited and involve the use of antibiotics and preservatives. Each of these agents has generally inadequate efficacy and a number of serious adverse effects. Thus, there is an urgent need for new antimicrobial drugs and food preservatives with higher efficacy and lower toxicity. Edible plants have been used in medicine since ancient times and are well known for their successful antimicrobial activity. Often photosensitizers are present in many edible plants; they could be a promising source for a new generation of drugs and food preservatives. The use of photodynamic therapy allows enhancement of antimicrobial properties in plant photosensitizers. The purpose of this review is to present the verified data on the antimicrobial activities of photodynamic phytochemicals in edible species of the world’s flora, including the various mechanisms of their actions.

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Section: Antimicrobial Properties Of Edible Plantsmentioning

confidence: 99%

Section: Antimicrobial Properties Of Edible Plantsmentioning

confidence: 99%

Antimicrobial Effect of Phytochemicals from Edible Plants

Hochma

Yarmolinsky²,

Khalfin

et al. 2021

Processes

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“…The antibacterial activity of BITC, for example, has been linked to protein damage triggered by benzyl isothiocyanates bioconjugation with cysteine, resulting in protein structure changes inactivating microbial growth [ 49 ] ( Figure 2 A). The antifungal activity of saponins has been reported to be linked with membrane dysfunction triggered by saponin’s complex formation with cholesterol, followed by cell death [ 39 ] ( Figure 2 B). On the other hand, the flavonoids can result in bacteriostatic and bactericidal effects [ 41 ]: it can promote bacterial cell aggregation (bacteriostatic effect), damage the cell membrane structure, inhibit the enzymatic activities of essential nutrients synthesis, and inhibit energy metabolism by inhibiting the enzymatic activity of the mitochondrial electron transport chain (e.g., NADH-cytochrome c reductase) (bactericidal effect) ( Figure 2 C).…”

Section: Green Preservatives By Natural Antimicrobials As Cheese Preservativementioning

confidence: 99%

“…Before discussing the antimicrobial effect of leading groups of natural antimicrobials able to inhibit the spoilage and pathogenic microbial development and growth in cheese, it is essential to understand, in a general manner, what the primary cellular mechanisms of action are. Among the different microbial metabolic signaling pathways reported to natural compounds, the most common toward natural antimicrobials include membrane permeability alteration [38,39], alterations of a cell wall structure [40], and alterations in metabolism (proteins and nucleic acids synthesis) by folic acid synthesis inhibition [41]. Then, cedar extract (Moringa oleifera) [42], basil EO (Ocimum basilicum L.) [43,44], oregano (Origanum vulgare L.), and rosemary (Rosmarinus officinalis) EOs [45] are just a few examples of natural antimicrobials of plant origin rich in bioactive compounds with bacteriostatic or bactericidal effects in cheese by mechanism routes cited above.…”

Section: Mechanisms Of Action Of Antimicrobials From Natural Originsmentioning

confidence: 99%

Green and Healthier Alternatives to Chemical Additives as Cheese Preservative: Natural Antimicrobials in Active Nanopackaging/Coatings

et al. 2021

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The side effects and potential impacts on human health by traditional chemical additives as food preservatives (i.e., potassium and sodium salts) are the reasons why novel policies are encouraged by worldwide public health institutes. More natural alternatives with high antimicrobial efficacy to extend shelf life without impairing the cheese physicochemical and sensory quality are encouraged. This study is a comprehensive review of emerging preservative cheese methods, including natural antimicrobials (e.g., vegetable, animal, and protist kingdom origins) as a preservative to reduce microbial cheese contamination and to extend shelf life by several efforts such as manufacturing ingredients, the active ingredient for coating/packaging, and the combination of packaging materials or processing technologies. Essential oils (EO) or plant extracts rich in phenolic and terpenes, combined with packaging conditions and non-thermal methods, generally showed a robust microbial inhibition and prolonged shelf life. However, it impaired the cheese sensory quality. Alternatives including EO, polysaccharides, polypeptides, and enzymes as active ingredients/nano-antimicrobials for an edible film of coating/nano-bio packaging showed a potent and broad-spectrum antimicrobial action during shelf life, preserving cheese quality parameters such as pH, texture, color, and flavor. Future opportunities were identified in order to investigate the toxicological effects of the discussed natural antimicrobials’ potential as cheese preservatives.

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“…9 They are classified into two main subclasses, steroidal, and terpenoid saponins, based on their different non-saccharide structures. 10 They are detergent-like natural surfactants showing biological activities against bacterial and fungal strains. Previous studies have reported the use of saponins as biodegradable and renewable alternatives to synthetic surfactants, 11 and recent research has demonstrated that saponins have a toxic effect against pathogenic bacteria.…”

Section: Introductionmentioning

confidence: 99%

Antibacterial and antibiofilm effects of Camellia oleifera seed dreg extract and its application in cosmetics

Yeh,

Sung,

Shih

2023

J of Cosmetic Dermatology

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BackgroundCosmetic care products contain a high proportion of water and nutrients. Therefore, preventing bacterial growth is an important issue to ensure product quality and safety. The application of antibacterial natural ingredients derived from plants is considered to have the potential to maintain product quality and reduce the use of chemicals in formulations. Additionally, chemically synthesized antiseptic and antibacterial agents are widely used in the industry at present. However, some preservative ingredients have been reported that may cause skin irritation, redness, allergies, and even dermatitis.AimsThis study aimed to prepare extract from Camellia oleifera tea seed dregs (CTSD), investigate the antibacterial effects on two pathogenic bacteria and evaluate the product preservative ability.MethodsEthanol extraction was prepared and subjected to characterize their triterpenoid contents. The minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and minimum biofilm eradication concentration (MBEC) were determined for Pseudomonas aeruginosa and Staphylococcus aureus. The product's stability and preservative qualities, along with its ability to scavenge free radicals through antioxidant activity, were also assessed.ResultsThe gram‐positive S. aureus showed greater susceptibility to the treatment. In additional, CTSD possessed significant free radical scavenging activity in vitro and cultured normal human skin fibroblast CCD‐966SK cells under nontoxic concentration. The challenge test and accelerated storage test confirmed the CTSD containing formulated emulsion is eligible for commercialization.ConclusionsCTSD has the potential to be developed as an alternative agent to control microbial biofilm formation, or can be used as an adjuvant compound for infectious disease control.

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Saponins Versus Plant Fungal Pathogens

Cited by 4 publications

References 28 publications

Antimicrobial Effect of Phytochemicals from Edible Plants

Antimicrobial Effect of Phytochemicals from Edible Plants

Green and Healthier Alternatives to Chemical Additives as Cheese Preservative: Natural Antimicrobials in Active Nanopackaging/Coatings

Antibacterial and antibiofilm effects of Camellia oleifera seed dreg extract and its application in cosmetics

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