The modeling and simulation of topography-induced imaging distortions are crucial for consistent radiometric information exploitation in current and forthcoming SAR-based Earth observation missions with a high spatial and temporal resolution, with relevance in several applications. In this paper, for the first time, we specifically investigate the compensation of topography-induced radiometric distortions affecting SAR images acquired by the L-band Argentinian satellite SAOCOM. We adopt a recently developed calibration method relying on an analytical formulation derived in the rigorous framework of the differential geometry of surfaces. We first provide an original interpretation of the analytical formulation, thus providing further insights into the relevant area-stretching-based formalism. Then, the numerical implementation of the method is specialized to systematically process the data acquired by SAOCOM sensors; hence, the resulting sensor-specific prototype solution processor is employed in this study. Finally, experiments performed over a real scenario in the southern part of Italy, characterized by large topography variations, are presented and discussed, thus elucidating the effectiveness of the adopted method applied to SAOCOM images. The adopted effective SAR calibration strategy opens up the way to its operational use in large-scale SAOCOM data processing.