Sarcoïdose gastro-intestinale

Màamouri, N.; Guellouz, S.; Hariz, F. Ben; Ketari, S.; Belkahla, N.; Ouerghi, H.; Chelly-Enneifer, I.; Chouaïb, S.; Zitouna, Moncef; Mami, N. Ben

doi:10.1016/j.revmed.2009.12.003

Cited by 12 publications

(3 citation statements)

References 6 publications

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“…Indeed, patients were suffering from intermittent diarrhea, constipation, hematochezia, abdominal pain, distention, vomiting, and weight loss [1–3, 5–7, 10]. In our case, the lesion was symptomatic of alternating constipation and diarrhea.…”

Section: Discussionmentioning

confidence: 69%

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Unusual Presentation of a Colonic Sarcoidosis

Daldoul¹,

Triki²,

Jeri

et al. 2012

Case Reports in Medicine

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Sarcoidosis is a multisystemic disorder of unknown cause that affects almost every tissue in the body. Colon is an extremely rare location of this disease. Clinical presentation, endoscopic appearances, and radiologic findings are not specific and may mimic much other affection. We report the case of a 64-year-old woman with inactive pulmonary sarcoidosis who presented alternating constipation and diarrhea. Colonoscopy revealed a stenotic tumor in the ascending colon. Histology failed to determine the nature of the lesion. Radiologic findings are those of a long stenotic tumor of the ascending colon associated with a multiple satellite lymphadenopathy. Endoscopic and radiologic descriptions are highly suggestive of a malignancy. The patient underwent a laparotomy, and a right hemicolectomy was performed. Examination of the resected specimen showed follicular structure with central epitheloid and giant cells and surrounding fibroblasts. These findings made the diagnosis of colonic sarcoidosis. The nonspecificity of the endoscopic and radiological signs of gastrointestinal sarcoidosis and the extreme rarity of colonic location make the preoperative diagnosis unlikely. The diagnosis will be then made only on histological examination of surgical specimens. We describe, through this observation, the results of paraclinical investigations that can suggest diagnosis and perhaps avoid surgery.

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Section: Discussionmentioning

confidence: 69%

“…In case of appearance pseudotumor, if biopsy specimens fail to demonstrate the diagnosis of colonic sarcoidosis, surgical treatment with conventional surgical oncologic principle must be proposed for fear of carcinoma [10]. …”

Section: Discussionmentioning

confidence: 99%

Unusual Presentation of a Colonic Sarcoidosis

Daldoul¹,

Triki²,

Jeri

et al. 2012

Case Reports in Medicine

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“…The prevalence of clinically recognizable gastrointestinal sarcoidosis has been estimated to range from 0.1% to 0.9% (2), with the stomach (particularly the gastric antrum) being the most common site of involvement. Duodenal involvement is particularly rare, with only a few cases of duodenal sarcoidosis documented in the literature (as indicated by a PubMed search using the terms 'duodenum AND sarcoidosis') (3)(4)(5)(6). A great number of cases of gastric sarcoidosis are clinically silent and may therefore be overlooked during upper endoscopy in the absence of abnormal gastric mucosa (7).…”

Section: Discussionmentioning

confidence: 99%

Upper Gastrointestinal Sarcoidosis: Report of Three Cases

et al. 2012

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Involvement of the upper gastrointestinal tract in sarcoidosis is rare, and an optimal treatment regimen remains to be determined. Here, we report 3 cases of upper gastrointestinal sarcoidosis in Japanese patients aged 57-70 years with or without epigastric symptoms and describe the clinical features, laboratory data, and upper endoscopy and pathological findings. Upper gastrointestinal sarcoidosis was diagnosed based on the presence of noncaseating epithelioid cell granuloma in the lamina propria in the stomach or duodenum. In conclusion, the possibility of upper gastrointestinal sarcoidosis should be considered in patients with epigastric symptoms and a history of sarcoidosis, even in those with stable disease.

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Sarcoidosis, Gastrointestinal

Rodrigues¹

2017

Encyclopedia of Pathology

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Sarcoïdose gastro-intestinale

Cited by 12 publications

References 6 publications

Unusual Presentation of a Colonic Sarcoidosis

Unusual Presentation of a Colonic Sarcoidosis

Upper Gastrointestinal Sarcoidosis: Report of Three Cases

Sarcoidosis, Gastrointestinal

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