Sarcoidosis and Cold Autoimmune Hemolytic Anemia: A Rare Association

Lorenzo, Noel; Merzouki, Tawoufik; Fuertes, Nuria; Saint-Mezard, Vanessa; Laboulbene, Stéphane

doi:10.4172/2329-8790.1000255

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2022

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“…A thorough historytaking and physical examination remain important along with a high index of suspicion. The commonest hematological abnormality in sarcoidosis (with or without bone marrow involvement) is anemia which may be either iron deficiency anemia or hemolytic anemia or anemia of chronic disease [7]. Leukopenia may be the only initial presentation which may be either due to bone marrow infiltration or hypersplenism and lymphocyte redistribution [8,9].…”

Section: Discussionmentioning

confidence: 99%

Isolated bone marrow sarcoidosis presenting as fever of unknown origin in a case of chronic myeloid leukemia

et al. 2022

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Background Isolated involvement of bone marrow in sarcoidosis has not been reported commonly. Sarcoidosis is a systemic granulomatous disease of unknown origin, characterized by the presence of non-caseating granulomatous lesions. There should be high index of suspicion in patients having underlying lymphoproliferative malignancies. Case presentation We present a 27-year-old male, known case of chronic myeloid leukemia, presenting as fever of unknown origin diagnosed with isolated bone marrow sarcoidosis.

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Section: Discussionmentioning

confidence: 99%