Sarcoidosis Mimicking a Malignant Metastatic Disease

Abstract

Sarcoidosis can have pulmonary and extrapulmonary clinical manifestations depending on the organ of involvement. Because multiple organs are involved by the disease, sarcoid can mimic metastatic diseases. Whenever clinical and radiological clues of metastasis are present, differentials other than cancer should not be missed. Herein, we present a case of a middle aged gentleman who presented to the oncology clinic for 1-month history of low back pain associated with a dry cough along with radiological findings of metastatic disease involving the lungs, liver, lymph nodes, axial spine, and adrenal gland. A biopsy of the liver lesion showed non-caseating granuloma. Elevated blood levels of angiotensin-converting enzyme confirmed the diagnosis of sarcoidosis.

Evaluation of sarcoidosis with multiple bone lesions using both bone scintigraphy and FDG-PET/CT: A case report

“…The short tubular bones of the hands and feet are most frequently involved in bone lesions of sarcoidosis and the vertebrae or pelvic bones are rarely involved. Table 2 summarizes previously reported cases of sarcoidosis with vertebral bone lesions, including the present case [ [4] , [5] , [6] , [7] , [8] , [9] , [10] , [11] , [12] , [13] , [14] , [15] , [16] , [17] , [18] ]. Among the 16 cases reported, 11 were symptomatic, and the symptom observed in all these cases was pain.…”

New-onset primary adrenal insufficiency in pregnancy associated with a unilateral adrenal infarction: a case report

“…Infectious etiologies of primary AI include tuberculosis, fungal infections and HIV. Infiltration of the adrenal glands by metastatic cancers, primary adrenal lymphoma, sarcoidosis or amyloidosis can lead to primary AI, which can be apparent on imaging ( 10 , 11 , 12 , 13 ). Bilateral adrenal hemorrhage can lead to the development of new-onset primary AI in pregnancy ( 14 ).…”