1996
DOI: 10.1097/00007890-199604150-00024
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Sarcoidosis Recurrence Following Lung Transplantation

Abstract: Sarcoidosis is a rare indication for lung transplantation. In this article, our experiences with recurring sarcoidosis following lung transplantation are described. Literature concerning recurrence of the disease in kidney, liver, heart and lung transmission of sarcoidosis via transplanted organs are discussed.

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Cited by 52 publications
(21 citation statements)
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“…Recurrent autoimmune disease has been suggested both after liver transplantation (such as for autoimmune hepatitis and for primary sclerosing cholangitis) and after transplantation of other organs, such as recurrent sarcoidosis in the lung 25 and autoimmune diabetes after pancreas transplantation. 26 Thus, if PBC is an autoimmune disease, it is not surprising that the disease recurs.…”
Section: What Does Recurrence Of Disease Mean For the Pathogenesis Ofmentioning
confidence: 99%
“…Recurrent autoimmune disease has been suggested both after liver transplantation (such as for autoimmune hepatitis and for primary sclerosing cholangitis) and after transplantation of other organs, such as recurrent sarcoidosis in the lung 25 and autoimmune diabetes after pancreas transplantation. 26 Thus, if PBC is an autoimmune disease, it is not surprising that the disease recurs.…”
Section: What Does Recurrence Of Disease Mean For the Pathogenesis Ofmentioning
confidence: 99%
“…Most interestingly, there are case reports of sarcoidosis patients who suffered from a relapse of sarcoidosis in a transplanted lung despite receiving immunosuppressive therapy [72][73][74]. Conversely, in two out of four cases patients receiving a lung or other organs from a donor who had a spontaneous remission of sarcoidosis in the past were observed to develop sarcoid-like lesions without suffering from sarcoidosis [73].…”
Section: Aetiologymentioning
confidence: 99%
“…Sarcoidosis, lymphangioleiomyomatosis, eosinophilic granulomatosis, panbronchiolitis, giant-cell interstitial pneumonia, bronchoalveolar cell carcinoma, emphysema, and desquamative interstitial pneumonia are among the diseases with case reports of recurring disease after lung transplantation. [5][6][7][8][9][10][11] Recurrence of veno-occlusive disease after transplantation has not been reported until now, and lung transplantation was thought to be definitive treatment for pulmonary veno-occlusive disease. With this 1st report of early recurrence after heart-lung transplantation, we believe that extrapulmonary factors may play a role in the pathogenesis of this disease.…”
Section: Discussionmentioning
confidence: 99%