Sarcoidosis subcutánea como primera manifestación de enfermedad sistémica

Nodules on the Forehead Associated With Generalized Lymphadenopathy

“…Although the lesions may be the first sign of the systemic sarcoidosis, it is more common for them to develop during the course of the disease; they are rarely an isolated finding. 4 The diagnosis is based on the clinical manifestations and histology, which reveals a predominantly lobular panniculitis with noncaseating epithelioid granulomas, with no peripheral lymphocytic corona, but with a large number of multinucleated giant cells. Schaumann (conchoidal) bodies and asteroid bodies may be seen; although these lesions are characteristic, they are not pathognomic of sarcoidosis.…”

Sarcoidose Subcutânea – Um Caso Raro De Manifestação Cutânea Específica

“…Nos doentes com poucas lesões cutâneas, a terapêutica pode ser realizada com corticóides intralesionais 8 , nos doentes cujo envolvimento seja mais extenso a corticoterapia sistémica é o tratamento de primeira escolha. Outras terapêuticas possíveis, em particular em doentes com contra indicação para medicação com corticóides são: metotrexato; hidroxicloroquina e colchicina 3 .…”