Sarcoidosis with polyarthritis in a child.

Schweizer, Anissa; Kanaar, P

doi:10.1136/adc.42.226.671

Cited by 15 publications

(5 citation statements)

References 8 publications

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“…The case reported by Schweizer and Kanaar (1967) exemplifies this peculiar group of cases. A male child aged 18 months developed an eruption of closely-packed papules on shoulder and hip areas, extending to trunk and face, biops y repeatedly showed sarcoid-type granulomas.…”

Section: Polyarthritis In Childrensupporting

confidence: 57%

“…Single cases of polyarthritis in young children with extensive sarcoidosis have been published by Burman and Mayer (1936), Zweifel (1946), Castellanos and Galan (1946), Schweizer and Kanaar (1967) and Toomey and Bautista (1970, Case 2), and six cases from several centres in the United Stares and Canada by North et al (1970). In all these 11 cases, the disease starred at a very early age, the first evidence of sarcoidosis appearing between four months and four years of age, and of arthropathy between nine months and four and a half years.…”

Section: Polyarthritis In Childrenmentioning

confidence: 99%

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Sarcoidosis

Scadding

Mitchell

1985

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Section: Polyarthritis In Childrensupporting

confidence: 57%

Section: Polyarthritis In Childrenmentioning

confidence: 99%

Sarcoidosis

Scadding

Mitchell

1985

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“…Although the patients described by these authors could have had distinct disorders, it is also possible that they had variant forms of sarcoidosis. Familial cases have been reported (12)(13)(14)(15)(16)(17), The mother of patient no, 3 was presumed to have JRA as a child, but could have had familial sarcoidosis with severe joint manifestations. All of our patients had clinical features that were not typical of adult sarcoidosis.…”

Section: Discussionmentioning

confidence: 99%

Sarcoidosis in Children: Differentiation from Juvenile Rheumatoid Arthritis

Mallory

Paller

Ginsburg

et al. 1987

Pediatric Dermatology

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Sarcoidosis is rare in young children, and is characterized by skin, joint, and eye changes. Differentiated clinically from juvenile rheumatoid arthritis (JRA) by milder constitutional symptoms and characteristic joint abnormalities, sarcoidosis is confirmed by demonstrating noncaseating granulomas in skin, conjunctival, or synovial biopsies. Recent reports have shown children with features of both sarcoidosis and juvenile rheumatoid arthritis, some with similarly affected family members. We cared for four children with sarcoidosis and severe joint manifestations. Two had a personal or family history of JRA. Three of the four children had ichthyosiform cutaneous manifestations, which may suggest an association between severe joint disease and ichthyosiform changes. Because of the difficulty in making a diagnosis on clinical grounds alone, biopsy of cutaneous lesions is recommended in children with these symptoms.

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“…Cron et al [5•] reported six children with arthritis, young age, and pulmonary involvement. Familial occurrence was reported in 1923 [6] with later reports describing many different combinations of parent-offspring and sib pairs [7][8][9][10][11][12][13] The disease is characterized by noncaseating granulomas, which are epithelial cell nodules associated with giant cells. Delayed type cutaneous hypersensitivity is depressed and a peripheral lymphopenia occurs [14].…”

Section: Introductionmentioning

confidence: 99%

Overview and report on international registry of sarcoid arthritis in childhood

Lindsley

Petty

2000

Curr Rheumatol Rep

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Interest in childhood sarcoidosis prompted the formation of an international registry in 1991. Over the next 5 years, 53 patients were registered by 23 physicians from 14 countries. All the patients had definite histologic evidence of sarcoidosis: noncaseating granulomas of the skin (31), synovium (15), liver (10), lymph node (eight), lung (five), muscle (four), conjunctiva (three), or kidney (one). All but nine patients developed polyarthritis; 38 of 44 had persistent arthritis. Of those with persistent polyarthritis, arthritis occurred at presentation in 16 of 38 patients and inflammation of the uveal tract of the eye occurred in 44 with involvement of both anterior and posterior segments in 21. One patient was blind at the time of the report. Other ocular complications included chorioretinitis, glaucoma, and phthisis bulbi. Laboratory abnormalities included mild anemia and elevated erythrocyte sedimentation rate (39 out of 45). Angiotensin converting enzyme levels were elevated in 14 out of 37 patients. Information on these patients with sarcoidosis helps develop a better understanding of this rare childhood disease. These patients are discussed in conjunction with an overview of sarcoid arthropathy.

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Sarcoidosis with polyarthritis in a child.

Cited by 15 publications

References 8 publications

Sarcoidosis

Sarcoidosis

Sarcoidosis in Children: Differentiation from Juvenile Rheumatoid Arthritis

Overview and report on international registry of sarcoid arthritis in childhood

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