Sarcomas of head and neck — A 10 yrs experience

Abstract

Abstract38 cases of sarcoma of head and neck region were analysed in a retrospective way in relation to age, anatomic location, histological, clinical profi le, and surgical approaches. Compared to other types of head and neck neoplasms, such as squamous cell carcinoma, soft tissue sarcomas have low rates of regional metastases. However the biological behaviour of soft tissue sarcoma is more aggressive specially in paediatric age group. In the present series, CT scan was considered as the primary modality of investigation. Surgery generally has been recommended as the primary method of treatment for achieving local control, except in those high-grade tumours arising in sites not amenable to resection. 3-year and 5-year survival rates in this present series 50% and 31.6% respectively.

Prevalence of Head and Neck Sarcomas in the Main Health Centers in Yazd from 1994 to 2014

“…In this study, more than half of the involved patients with the head and neck sarcomas (56%) were females, which is in line with the findings by Bree et al (27) , although in several other studies (23,(28)(29)(30)(31) men have been reported to be affect-Discussion neck neoplasms (e.g., squamous cell carcinoma), soft tissue sarcomas have a lower rate of regional metastasis. (39) In this study, only 2 cases (3.4%) had metastasis to other parts of the body, whereas in a study conducted by Tajudeen et al (9) metastasis to lymph nodes was 6.5% and neural invasion was observed in 6.5% of the cases. Salcedo-Hernández et al (5) reported 50% of soft tissue sarcomas of the head and neck involving metastasis.…”

Oral Spindle Cell Sarcoma: A Rare Case Report and Review of Literature

“…Ocular symptoms include diplopia, unilateral tearing, and fullness of lids, orbital pain and also exophthalmos. Facial symptoms include paraesthesia over the infraorbital nerve, swelling and pain over cheek and facial asymmetry as seen in our case [1,3]. This case is presented for its uniqueness of occurrence at a comparatively younger age, site and aggressive nature of presentation.…”

“…Sarcomas are rare tumours usually heterogeneous by nature, largely originating from the embryonic mesoderm accounting for less than 1% of all head and neck primary cancers [1]. Numerous studies have reported that oral sarcomas represent 0.14%-27.7% of all head and neck cancers suggestive of rarity of the tumour [2][3][4].…”

“…All cases should be treated aggressively with surgical therapy has been the mainstay in the management (maxillectomy with lymph node dissection), and adjuvant (chemo) radiotherapy should be considered in patients with high risk behaviour. Whole tumour removal e.g., total maxillectomy may produce poor cosmetic and functional results due to its vicinity to vital structures [1]. Since spindle cell sarcomas of the head and neck region are a rare entity, evidence of optimal management is lacking.…”

“…Since spindle cell sarcomas of the head and neck region are a rare entity, evidence of optimal management is lacking. Head and neck sarcomas have poor prognosis as compared to other body sites [1,7]. However, despite efforts at early initiation of therapy our patient couldn't survive because of the aggressive nature of the disease.…”