Sarcomatoid variant of urothelial carcinoma in the renal pelvis with brain metastasis: a case report

Nasrollahi, Hamid; Ahmed, Faisal; Eslahi, Ali; Pilehroud, Mehrdad Golmoradi; Safaei, Akbar; Askarpour, Mohammad Reza; Khorshidi, AbdolAzim; Khorshidi, Soorena

doi:10.11604/pamj.2022.41.233.31688

Cited by 2 publications

(4 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…SUC is a rare and highly aggressive tumor type that accounts for 0.3% of all UC cases ( 1 ). SUC generally developed in the bladder, and reports of SUCs in the renal pelvis are extremely rare ( 4 ), with such descriptions largely confined to individual case reports.…”

Section: Discussionmentioning

confidence: 99%

“…in 1984 ( 5 ). For a systematic overview of all cases of SUCs of the renal pelvis published after the year 2000, see Table 1 ( 1 , 2 , 4 , 6 – 21 ).…”

Section: Discussionmentioning

confidence: 99%

“…Renal pelvis carcinomas primarily arise in the form of transitional cell carcinomas arising from the urinary tract epithelium. SUC is a rare tumor type that accounts for just 0.3% of all urothelial carcinoma (UC) cases ( 1 ). SUCs are highly invasive, progress rapidly, and are generally associated with a very poor patient prognosis ( 2 ).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Case report: Sarcomatoid urothelial carcinoma of the renal pelvis masquerading as a renal abscess

et al. 2023

View full text Add to dashboard Cite

Sarcomatoid urothelial carcinoma (SUC), a rare tumor of the urinary tract epithelium, exhibits a high degree of malignancy and therefore a poor prognosis. Due to the absence of specific clinical presentations and imaging findings, SUC of the renal pelvis masquerades as a renal abscess is frequently under-recognized or misdiagnosed as benign inflammatory disease, resulting in delayed or erroneous treatment. Here, we report a patient with SUC of the renal pelvis who presented with a renal abscess. Repeated anti-inflammatory treatment was ineffective. Unexpectedly, cancerous cells were detected in subsequent exfoliative cytology of nephrostomy drainage fluid. In accordance with this, radical surgery and postoperative chemotherapy were conducted. Fortunately, neither recurrence nor metastasis occurred during a one-year follow-up.

show abstract

Section: Discussionmentioning

confidence: 99%

“…in 1984 ( 5 ). For a systematic overview of all cases of SUCs of the renal pelvis published after the year 2000, see Table 1 ( 1 , 2 , 4 , 6 – 21 ).…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Case report: Sarcomatoid urothelial carcinoma of the renal pelvis masquerading as a renal abscess

et al. 2023

View full text Add to dashboard Cite

show abstract

“…A sarcomatoid variant is an uncommon form of urothelial carcinoma, comprising less than 0.5% of all urothelial cancers in the bladder. Patients usually present with complaints of lower urinary tract symptoms and hematuria [ 1 ]. The tumor cells of the sarcomatoid variant have cytological, histological, and molecular properties of the biphasic components, epithelial (carcinoma) and mesenchymal (sarcoma), with the presence or absence of heterologous elements [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

Exploring the Rare Case of a Sarcomatoid Variant of Urothelial Carcinoma

Kani,

Chander R

2024

Cureus

View full text Add to dashboard Cite

A sarcomatoid variant of urothelial carcinoma (SVUC) is an extremely rare variant, which accounts for only 0.1-0.3% of all urothelial carcinomas of the bladder. SVUC is distinguished by the presence of biphasic components; there can be morphological and/or immunohistochemical substantiation of epithelial and mesenchymal differentiation. The patients with this variant have been associated with very poor disease-specific and overall survival rates in comparison with the high-grade pure urothelial carcinoma. Being a rare entity, it usually presents at a higher grade and is related to a dismal prognosis in comparison with conventional urothelial carcinoma. Careful examination, early diagnosis, and effective treatment are the most important steps for good survival. Here, we report a 58-year-old male who presented with complaints of hematuria for one and a half months with histopathology showing features of SVUC.

show abstract

Sarcomatoid variant of urothelial carcinoma in the renal pelvis with brain metastasis: a case report

Cited by 2 publications

References 12 publications

Case report: Sarcomatoid urothelial carcinoma of the renal pelvis masquerading as a renal abscess

Case report: Sarcomatoid urothelial carcinoma of the renal pelvis masquerading as a renal abscess

Exploring the Rare Case of a Sarcomatoid Variant of Urothelial Carcinoma

Contact Info

Product

Resources

About