Sarcopenia among hospitalized patients – A cross-sectional study

Sousa, Ana; Guerra, Rita S.; Fonseca, Isabel; Pichel, Fernando; Amaral, Teresa

doi:10.1016/j.clnu.2014.12.015

Cited by 69 publications

(57 citation statements)

References 24 publications

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“…The association of a high risk of malnutrition and lower muscle mass at admission is in line with a cross-sectional cohort study of 608 hospitalized patients with a significantly younger age compared to our cohort (median age 57 years) [26]. The prevalence of sarcopenia (i.e.…”

Section: Discussionsupporting

confidence: 87%

High risk of malnutrition is associated with low muscle mass in older hospitalized patients - a prospective cohort study

et al. 2017

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BackgroundMalnutrition, low muscle strength and muscle mass are highly prevalent in older hospitalized patients and associated with adverse outcomes. Malnutrition may be a risk factor for developing low muscle mass. We aimed to investigate the association between the risk of malnutrition and 1) muscle strength and muscle mass at admission and 2) the change of muscle strength and muscle mass during hospitalization in older patients.MethodsThe EMPOWER study included 378 patients aged seventy years or older who were acutely or electively admitted to four different wards of an academic teaching hospital in Amsterdam. Patients were grouped into low risk of malnutrition and high risk of malnutrition based on the Short Nutritional Assessment Questionnaire (SNAQ) score and were assessed for hand grip strength and muscle mass using hand held dynamometry respectively bioelectrical impedance analysis (BIA) within 48 h after admission and at day seven, or earlier at the day of discharge. Muscle mass was expressed as skeletal muscle mass, appendicular lean mass, fat free mass and the skeletal muscle index.ResultsThe mean age of the patients was 79.7 years (SD 6.39), 48.9% were female. At admission, being at high risk of malnutrition was significantly associated with lower muscle mass (Odds Ratio, 95% CI, 0.90, 0.85–0.96), but not with muscle strength. Muscle strength and muscle mass did not change significantly during hospitalization in both groups.ConclusionIn older hospitalized patients, a high risk of malnutrition is associated with lower muscle mass at admission, but not with muscle strength nor with change of either muscle strength or muscle mass during hospitalization.

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Section: Discussionsupporting

confidence: 87%

High risk of malnutrition is associated with low muscle mass in older hospitalized patients - a prospective cohort study

et al. 2017

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“…Low muscle mass was associated with increased prevalence of delirium in older participants living in nursing homes [12] . Low muscle mass and muscle strength were associated with increased prevalence of falls in the past year in community-dwelling older adults [13] and in older outpatients [23] , and with dependence in ADL and malnourishment in older hospitalized patients [14] . A recent systematic review summarized the negative consequences of sarcopenia, including falls, functional limitations, functional decline, and mortality in various older populations [24] .…”

Section: Discussionmentioning

confidence: 99%

Muscle Strength and Muscle Mass in Older Patients during Hospitalization: The EMPOWER Study

et al. 2017

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Background: Low muscle strength and muscle mass are associated with an increased length of hospital stay and higher mortality rate in inpatients. To what extent hospitalization affects muscle strength and muscle mass is unclear. Objective: We aimed to assess muscle strength and muscle mass at admission and during hospitalization in older patients and its relation with being at risk of geriatric conditions. Methods: The EMPOWER study included patients aged 70 years and older, admitted to 4 wards of the VU University Medical Center in the Netherlands between April and December 2015. At admission, patients were screened for being at risk of 4 geriatric conditions: delirium, falls, malnutrition, and functional disability. At admission and at discharge, muscle strength and muscle mass were assessed. Results: A total of373 patients (mean age, standard deviation [SD]: 79.6, 6.38 years) were included at admission, and 224 patients (mean age, SD: 80.1, 6.32 years) at discharge. At admission, lower muscle strength in both female and male patients and low muscle mass in male patients were associated with being at risk of a higher cumulative number of geriatric conditions. Muscle strength increased during hospitalization, but no change in muscle mass was observed. Changes in muscle measures were not associated with being at risk of geriatric conditions. Discussion: Older patients with lower muscle strength and muscle mass at admission were at risk of a higher cumulative number of geriatric conditions. However, being at risk of geriatric conditions did not forecast further decrease in muscle strength and muscle mass during hospitalization

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“…Sarcopenia, a geriatric syndrome associated with the decline of muscle mass and strength, 1 is a predictor of poor outcomes, including mortality, disability, and poor quality of life 1 – 3 . The prevalence of sarcopenia differs among settings, with values of 1%–40% in community‐dwelling elderly, 4 – 6 29%–85% in institutionalized elderly, 7 – 9 and 22%–37% in hospitalized patients 2 , 10 – 13 . Diagnostic methods for sarcopenia commonly rely on measurements of muscle mass, gait speed, physical performance, and handgrip strength (HGS).…”

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confidence: 99%

“…Most studies in elderly individuals in the institutional and hospital settings exclude those who cannot walk or are bedridden and do not include HGS assessments 2 , 7 – 13 . However, the elderly in these settings more frequently exhibit physical dysfunction in ambulatory status 16 – 19 ; they need help to walk, use wheelchairs, or are immobile.…”

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confidence: 99%

Sarcopenia Is Highly Prevalent in Older Medical Patients With Mobility Limitation

Maeda

Shamoto²,

Wakabayashi

et al. 2016

Nut in Clin Prac

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Sarcopenia among hospitalized patients – A cross-sectional study

Cited by 69 publications

References 24 publications

High risk of malnutrition is associated with low muscle mass in older hospitalized patients - a prospective cohort study

High risk of malnutrition is associated with low muscle mass in older hospitalized patients - a prospective cohort study

Muscle Strength and Muscle Mass in Older Patients during Hospitalization: The EMPOWER Study

Sarcopenia Is Highly Prevalent in Older Medical Patients With Mobility Limitation

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