Sarcopenia and its associated factors in Iranian older individuals: Results of SARIR study

Hashemi, Rezvan; Shafiee, Gita; Motlagh, Ahmadreza Dorosty; Pasalar, Parvin; Esmailzadeh, Ahmad; Siassi, Fereydoun; Larijani, Bagher; Heshmat, Ramin

doi:10.1016/j.archger.2016.04.016

Cited by 54 publications

(45 citation statements)

References 34 publications

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“…The test is repeated twice, with the best time used for scoring. The cut-off value is ≤0.8 m/s, based on data from the study in 1,030 men and women of a wide-age range [ 22 , 30 , 37 ]. Limitations for the walking test include mental impairment (assessed using the Mini Mental State Examination), history of chronic diseases such as stroke, congestive heart failure, Parkinson's Disease, active cancer, and neuropathy, inability to walk without crutches, and/or the presence of artificial limbs or prostheses [ 30 , 37 ].…”

Section: Proposed Identification and Diagnosis Of Osteosarcopenic mentioning

confidence: 99%

“…The test is repeated twice, with the best time used for scoring. The cut-off value is ≤0.8 m/s, based on data from the study in 1,030 men and women of a wide-age range [ 22 , 30 , 37 ].…”

Section: Proposed Identification and Diagnosis Of Osteosarcopenic mentioning

confidence: 99%

“…Limitations for the walking test include mental impairment (assessed using the Mini Mental State Examination), history of chronic diseases such as stroke, congestive heart failure, Parkinson's Disease, active cancer, and neuropathy, inability to walk without crutches, and/or the presence of artificial limbs or prostheses [ 30 , 37 ].…”

Section: Proposed Identification and Diagnosis Of Osteosarcopenic mentioning

confidence: 99%

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Osteosarcopenic Obesity Syndrome: What Is It and How Can It Be Identified and Diagnosed?

Ilich

Kelly

Inglis

2016

Current Gerontology and Geriatrics Research

100

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Conditions related to body composition and aging, such as osteopenic obesity, sarcopenia/sarcopenic obesity, and the newly termed osteosarcopenic obesity (triad of bone muscle and adipose tissue impairment), are beginning to gain recognition. However there is still a lack of definitive diagnostic criteria for these conditions. Little is known about the long-term impact of these combined conditions of osteoporosis, sarcopenia, and obesity in older adults. Many may go undiagnosed and progress untreated. Therefore, the objective of this research is to create diagnostic criteria for osteosarcopenic obesity in older women. The proposed diagnostic criteria are based on two types of assessments: physical, via body composition measurements, and functional, via physical performance measures. Body composition measurements such as T-scores for bone mineral density, appendicular lean mass for sarcopenia, and percent body fat could all be obtained via dual energy X-ray absorptiometry. Physical performance tests: handgrip strength, one-leg stance, walking speed, and sit-to-stand could be assessed with minimal equipment. A score could then be obtained to measure functional decline in the older adult. For diagnosing osteosarcopenic obesity and other conditions related to bone loss and muscle loss combined with obesity, a combination of measures may more adequately improve the assessment process.

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Section: Proposed Identification and Diagnosis Of Osteosarcopenic mentioning

confidence: 99%

“…The test is repeated twice, with the best time used for scoring. The cut-off value is ≤0.8 m/s, based on data from the study in 1,030 men and women of a wide-age range [ 22 , 30 , 37 ].…”

Section: Proposed Identification and Diagnosis Of Osteosarcopenic mentioning

confidence: 99%

Section: Proposed Identification and Diagnosis Of Osteosarcopenic mentioning

confidence: 99%

See 1 more Smart Citation

Osteosarcopenic Obesity Syndrome: What Is It and How Can It Be Identified and Diagnosed?

Ilich

Kelly

Inglis

2016

Current Gerontology and Geriatrics Research

100

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“…Sarcopenia, the age-related loss of skeletal muscle mass and strength [ 23 ], has shown to be influenced by several lifestyle habits including reduced physical activity [ 24 – 26 ], alcohol consumption [ 27 , 28 ], and smoking of tobacco [ 29 , 30 ]. The negative effect of alcohol consumption is though contradicted by Steffl et al [ 31 ].…”

Section: Introductionmentioning

confidence: 99%

Effects of Lifestyle on Muscle Strength in a Healthy Danish Population

Bartels¹,

Robertson²,

Danneskiold‐Samsøe³

et al. 2018

J Lifestyle Med

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BackgroundLifestyle is expected to influence muscle strength. This study aimed at assessing a possible relationship between smoking, alcohol intake and physical activity, and muscle strength in a healthy Danish population aged 20–79 years. Population study based on data collected from The Copenhagen City Heart Study (CCHS) and measurements of Isokinetic muscle strength from a sub-study of randomly selected healthy participants from CCHS.Methods126 women and 63 men were studied. All participants completed a questionnaire regarding their lifestyle, including physical activity, alcohol intake and smoking habits. Isokinetic muscle strength was measured over the upper extremities (UE), trunk, and lower extremities (LE). Multivariate analyses including all of the variables were carried out.ResultsThe level of daily physical activity during leisure was positively correlated to muscle strength in the lower extremities (p = 0.03) for women, and lower extremities (p = 0.03) and trunk (p = 0.007) for men. Alcohol Intake was in general not correlated to muscle strength. No clear effect of smoking was seen on muscle strength.ConclusionOur results show that physical activity during leisure is associated with a positive effect on muscle strength in both sexes. When keeping alcohol intake within the recommended limits, alcohol does not seem to affect muscle strength negatively. No effect of smoking on muscle strength was found in our group of healthy subjects. The findings are of importance when considering recommendation on life style when wishing to keeping fit with age to be able to carry out daily activities.

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“…Sarcopenia in the elderly is identified on the basis of hand muscle strength (fingers and forearm flexor) less than 26-30 kg, the ability to walk 4 m in less than 0.8 m/s, and muscle mass index among young population with an average less than 2 standard deviations. 18 After filling out the consent form and verifying the health status and exercise history, the subjects were grouped based on muscle hand strength less than 26-30 kg, and were randomly divided into 4 equal groups: Resistance training and leucine supplemental (RTLS), resistance training (RT), leucine supplementation (LS), and control (C). Exclusion criteria included a history of chronic diseases (heart failure, chronic obstructive lung, kidney failure, cancer, diabetes, anemia, and thyroid disease), drug or supplementation (such as corticosteroids and anabolic hormones), inability to exercise, and a regular exercise history (3 times a week, more than 30 minutes).…”

Section: Subjectsmentioning

confidence: 99%

The Effect of 8-Week Resistance Training and Leucine Supplementation on Protein Synthesis Among Elderly Men With Sarcopenia

Pormozafari

Aminaie

Nikooie

2018

Int J Basic Sci Med

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Introduction: The aim of present study was to determine the effect of eight weeks resistance training and the supplementation of leucine on protein synthesis in the elderly men with sarcopenia. Methods: A total of 40 elderly men residing in the elderly nursing center were randomly chosen and divided into four groups including Resistance Training and Leucine Supplement (RTLS=10), Resistance Training (RT=10), Leucine Supplement (LS=10), and Control (C=10). Resistance training was performed 8 weeks with intensity training %35-70 of one repetition maximum (1RM) for 20-45 minutes. The group supplement consumed 3 grams of leucine amino acid in every meal. The serum insulin concentration, urine nitrogen, muscle mass, and muscle strength were measured one day before the protocol and 72 hours after the last training session. Ancova was analyzed within and between group changes. Bonferroni post hoc test was used to determine the difference between every two groups. Results: Results showed that Urine nitrogen and muscle mass levels increased significantly after 8 weeks of RT compared to the C group (p<0.05). Serum insulin concentration increased significantly in the RT group compared with the C group (p<0.05). There was a significant increase in muscle strength in the RT and S group compared to the C group (p<0.05). Conclusion: The results of this study revealed that the muscle protein synthesis increased after resistance training in skeletal muscle. This indicates that the rate of sarcopenia reduced as a result of resistance training. In addition, resistance training along with consuming leucine supplement was effective in improving muscle strength.

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Sarcopenia and its associated factors in Iranian older individuals: Results of SARIR study

Cited by 54 publications

References 34 publications

Osteosarcopenic Obesity Syndrome: What Is It and How Can It Be Identified and Diagnosed?

Osteosarcopenic Obesity Syndrome: What Is It and How Can It Be Identified and Diagnosed?

Effects of Lifestyle on Muscle Strength in a Healthy Danish Population

The Effect of 8-Week Resistance Training and Leucine Supplementation on Protein Synthesis Among Elderly Men With Sarcopenia

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