Sarcopenia is associated with worse recovery of physical function and dysphagia and a lower rate of home discharge in Japanese hospitalized adults undergoing convalescent rehabilitation

Yoshimura, Yoshihiro; Wakabayashi, Hidetaka; Bise, Takahiro; Nagano, Fumihiko; Shimazu, Sayuri; Shiraishi, Ai; Yamaga, Makio; Koga, Hiroaki

doi:10.1016/j.nut.2018.11.005

Cited by 169 publications

(154 citation statements)

References 53 publications

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“…The presence of sarcopenia was independently associated with FIM‐M at discharge in only male patients, whereas this relationship was not found in female patients. These findings are inconsistent with the previous studies that showed a significant relationship between sarcopenia and motor FIM at discharge in both sexes . This discrepancy might be attributed to the nature of the present study population, because we did not include patients who transferred to acute care hospitals due to aggravated clinical conditions.…”

Section: Discussioncontrasting

confidence: 97%

“…In the present study, the sample size was calculated using the Power and Sample Size Calculation software version 3.0 (William D Dupont PhD and Walton D Plummer, Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN, USA). The ratio of the stroke patients with and without sarcopenia was expected to be 1 . We intended to detect 10 points of FIM‐M according to the value used in a previous study .…”

Section: Methodsmentioning

confidence: 99%

“…The ratio of the stroke patients with and without sarcopenia was expected to be 1 . We intended to detect 10 points of FIM‐M according to the value used in a previous study . If the standard deviation of FIM‐M was set as 25.2, at least 101 patients from each group would be required to achieve 80% power and a type I error probability of 0.05 .…”

Section: Methodsmentioning

confidence: 99%

“…Indeed, patients with stroke‐related sarcopenia have lower ADL scores than those without this condition . In addition, sarcopenia in stroke patients might predict their ADL capabilities at discharge from convalescent rehabilitation wards . However, whether sarcopenia affects the ADL of stroke patients who completed a comprehensive rehabilitation program remains unclear, because a previous study did not exclude patients who were discharged to acute care hospitals .…”

Section: Introductionmentioning

confidence: 99%

“…10,12,13 In addition, sarcopenia in stroke patients might predict their ADL capabilities at discharge from convalescent rehabilitation wards. 14 However, whether sarcopenia affects the ADL of stroke patients who completed a comprehensive rehabilitation program remains unclear, because a previous study did not exclude patients who were discharged to acute care hospitals. 14 Additionally, at this point, the impact of the new diagnostic criteria of sarcopenia published by the European Working Group on Sarcopenia in Older People (EWGSOP2) largely remains to be seen.…”

Section: Introductionmentioning

confidence: 99%

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Sarcopenia as a predictor of activities of daily living capability in stroke patients undergoing rehabilitation

Matsushita¹,

Nishioka²,

Taguchi³

et al. 2019

Geriatrics Gerontology Int

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Aim The aim of the present study was to clarify the relationship between sarcopenia, as defined by the European Working Group on Sarcopenia in Older People, and the recovery of the capability to carry out activities of daily living in convalescent stroke patients who completed a rehabilitation program. Methods This retrospective study included consecutive stroke patients admitted to convalescent rehabilitation wards. To determine which patients had sarcopenia, we used the European Working Group on Sarcopenia in Older People criteria. At admission, participants were classified by either the presence or absence of sarcopenia. Baseline characteristics, including the Functional Independence Measure–motor domain score (FIM‐M), were retrospectively analyzed. The primary outcome to be explained was the FIM‐M at discharge. A multiple linear regression analysis was used to examine how well a sarcopenia diagnosis and various baseline characteristics could predict the FIM‐M score at discharge. Results In total, 267 participants (117 women) were included in this study. Of these, 129 (48.3%) were classified as definitely having sarcopenia. Participants with sarcopenia showed lower FIM‐M at discharge than those without this condition (median 72 vs 89, P < 0.001). Multiple linear regression analyses exploring determinants of the FIM‐M scores showed that a diagnosis of sarcopenia independently predicted them at discharge for men (B −4.957, 95% confidence interval −9.902–−0.012), but not for women. Conclusions Stroke‐related sarcopenia appears to be a predictor of how well male patients can engage in activities of daily living after rehabilitation. Geriatr Gerontol Int 2019; 19: 1124–1128.

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Section: Discussioncontrasting

confidence: 97%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Sarcopenia as a predictor of activities of daily living capability in stroke patients undergoing rehabilitation

Matsushita¹,

Nishioka²,

Taguchi³

et al. 2019

Geriatrics Gerontology Int

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Validation of a proxy‐reported SARC‐F questionnaire for current and retrospective screening of sarcopenia‐related functional impairments

Maurus

Terzer

Benner

et al. 2021

J cachexia sarcopenia muscle

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BackgroundThe strength, assistance walking, rise from a chair, climb stairs, and falls (SARC-F) questionnaire is a well-established instrument for screening of sarcopenia and sarcopenia-related functional impairments. As it is based on self-reporting, its use precludes patients who are unable to answer the questionnaire as a consequence of severe acute diseases or cognitive impairment. Therefore, we aimed to validate a proxy-reported version of the SARC-F for both ad-hoc as well as retrospective screening for severe sarcopenia-related functional impairments. Methods Patients aged ≥60 years completed the SARC-F and performed the short physical performance battery (SPPB) at baseline (T1). Proxies in Cohort A gave a simultaneous assessment of the patients' functional status with the proxy-reported SARC-F at T1 and again, retrospectively, after 3 months (T2). Proxies in Cohort B only completed the SARC-F retrospectively at T2. The questionnaires' performances were assessed through sensitivity/specificity analyses and receiver operating characteristic (ROC) curves. For non-inferiority analyses, results of both the patient-reported and proxy-reported SARC-F were correlated with the SPPB total score as well as the results of the chair-rise test subcategory; the respective correlation coefficients were tested against each other. Results One hundred and four patients and 135 proxies participated. Using a SPPB score < 9 points as the reference standard, the proxy-reported SARC-F identified patients at high risk for sarcopenia-related functional impairment with a sensitivity of 0.81 (ad-hoc), 0.88 (retrospective Cohort A), and 0.87 (retrospective Cohort B) as well as a specificity of 0.89 (ad-hoc), 0.78 (retrospective Cohort A), and 0.64 (retrospective Cohort B). Areas under the ROC curves were ≥ 0.9 for the ad-hoc proxy-reported SARC-F and the retrospective proxy-reported SARC-F in both cohorts. The proxy-reported SARC-F showed a non-inferior correlation with the SPPB compared with the patient-reported SARC-F for ad-hoc (P = <0.001) as well as retrospective screening for severe sarcopenia-related functional impairment in both Cohorts A (P = 0.007) and B (P = 0.026). Conclusions Proxy-reported SARC-F is a valid instrument for both ad-hoc as well as retrospective screening for sarcopenia-related functional impairment and could become the standard tool for evaluating this risk in older adults with severe acute disease, for example, in patients with quickly evolving haematological conditions.

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Goal setting for nutrition and body weight in rehabilitation nutrition: position paper by the Japanese Association of Rehabilitation Nutrition (secondary publication)

Wakabayashi

Yoshimura²,

Maeda

et al. 2021

J of Gen and Family Med

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Rehabilitation nutritional care involves setting rehabilitation nutrition goals, 1-3 including both rehabilitation and nutrition goals. Rehabilitation goals often encompass improvements in functions including body function and structure, activity, and participation. Nutrition goals, on the contrary, include improvements in not only body weight, muscle mass, and body fat but also muscle strength, physical function, swallowing function, activities of daily living (ADL), quality of life (QOL), and participation. The most important of these nutrition goals are improving function and QOL. However, at present, setting nutrition goals by body weight makes it easier to calculate daily energy requirements. Therefore, in this position paper, we clarified our position, as the Japanese Association of Rehabilitation Nutrition, on the existing knowledge of how to set body weight goals.

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Sarcopenia is associated with worse recovery of physical function and dysphagia and a lower rate of home discharge in Japanese hospitalized adults undergoing convalescent rehabilitation

Cited by 169 publications

References 53 publications

Sarcopenia as a predictor of activities of daily living capability in stroke patients undergoing rehabilitation

Sarcopenia as a predictor of activities of daily living capability in stroke patients undergoing rehabilitation

Validation of a proxy‐reported SARC‐F questionnaire for current and retrospective screening of sarcopenia‐related functional impairments

Goal setting for nutrition and body weight in rehabilitation nutrition: position paper by the Japanese Association of Rehabilitation Nutrition (secondary publication)

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