Sarcopenic obesity by the ESPEN/EASO criteria for predicting mortality in advanced non-small cell lung cancer

Zhou, Jinqiu; Luo, Lanxin; Xie, Li; Hu, Song; Lu, Tan; Lei, Xiaoqiang; Luo, Xiaozhen; Yang, Ming

doi:10.1016/j.clnu.2023.04.010

Cited by 12 publications

(7 citation statements)

References 35 publications

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“…The consistency between the two diagnostic criteria demonstrated good agreement (Cohen’s kappa = 0.759). This finding aligns with our prior study, indicating excellent agreement between SO ESPEN and SO ESPEN−M in patients with non-small cell lung cancer [ 9 ].…”

Section: Discussionsupporting

confidence: 92%

“…After the release of the ESPEN/EASO consensus, some studies have embraced this definition and diagnostic criteria across various study populations, including stoke [ 24 ], rehabilitation [ 25 ], post-bariatric surgery [ 26 ], cancer [ 9 ], and community-dwelling older adults [ 5 , 27 ]. The reported prevalence of SO ESPEN in these studies ranged from 4.3 to 31.9%, whereas it reached 43.5% in our study population.…”

Section: Discussionmentioning

confidence: 99%

“…For example, Bahat et al [ 15 ] reported that SMM/BMI, compared to SMM/W, exhibited a stronger association with functional disability in community-dwelling older adults aged ≥ 60 years. Additionally, our prior study demonstrated that SMM/BMI was a better predictor of mortality than SMM/W in patients with non-small cell lung cancer [ 9 ]. In the present study, both SMM/W and SMM/BMI were significantly lower in participants with IADL disability compared to participants without IADL disability.…”

Section: Discussionmentioning

confidence: 99%

“…Body composition was measured by a trained nurse with a multi-frequency segmental bioimpedance analysis (BIA) device (InBody 770, Biospace, Seoul, Korea). The details regarding the measurement of body composition with the BIA device have been reported previously [ 9 ]. SMM and fat mass (FM) were measured using the BIA device.…”

Section: Methodsmentioning

confidence: 99%

“…Therefore, the European Society for Clinical Nutrition and Metabolism (ESPEN) and the European Association for the Study of Obesity (EASO) [ 8 ] recently proposed the first international definition and diagnostic criteria for SO, which needs to be validated in different clinical settings. Our team has revealed that the ESPEN/EASO-defined SO (SO ESPEN ) was an independent prognostic factor for mortality in patients with advanced non-small cell lung cancer [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

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Sarcopenic obesity in nursing home residents: a multi-center study on diagnostic methods and their association with instrumental activities of daily living

Tang,

Li,

et al. 2024

BMC Geriatr

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Background Sarcopenic obesity (SO) in nursing home residents is rarely studied. We aimed to evaluate and compare the prevalence and consistency of different SO diagnostic methods and to investigate which criterion demonstrated a stronger association with instrumental activities of daily living (IADL) disability. Methods We consecutively recruited older adults aged ≥ 60 years, residing in 15 nursing homes in Zigong City, China. Sarcopenia obesity was defined according to the European Society for Clinical Nutrition and Metabolism (ESPEN) and the European Association for the Study of Obesity criteria (SOESPEN), recommending skeletal muscle mass (SMM) adjusted by body weight (SMM/W) to identify low muscle mass. Further, we adapted ESPEN criteria (SOESPEN−M) by employing SMM adjusted by body mass index (SMM/BMI). Results We included 832 participants (median age 73.0 years, 296 women). The prevalence of SOESPEN and SOESPEN−M was 43.5% and 45.3%, respectively. SOESPEN showed good consistency with SOESPEN−M (Cohen’s kappa = 0.759). More than one-third of participants in the normal weight group were diagnosed with SOESPEN or SOESPEN−M. Even within the underweight group, the prevalence of SOESPEN and SOESPEN−M was 8.9% and 22.2%, respectively. Participants with IADL disability had significantly lower SMM/W and SMM/BMI, but higher fat mass percentage of body weight (FM%) than participants without IADL disability. After full adjustment for potential confounders, SOESPEN−M (OR 1.68, 95% CI 1.21 to 2.32), but not SOESPEN (OR 1.28, 95% CI 0.93 to 1.75), remained significantly associated with IADL disability. Conclusions Both SOESPEN and SOESPEN−M showed a high prevalence among nursing home residents, even among individuals with underweight or normal weight. While SOESPEN had a good consistency with SOESPEN−M, only SOESPEN−M was independently associated with IADL disability. Screening and diagnosis of SO should be conducted in nursing home residents irrespective of BMI.

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Section: Discussionsupporting

confidence: 92%