SARS-CoV-2 in asymptomatic pregnant women in South Brazil: RT-PCR and serological detection

Chiste, Jullie Anne; Furuie, Isabella Naomi; Nogueira, Meri Bordignon; Longo, Jessica da Silva; Fugaça, Cyllian Arias; Cavalli, Bárbara Maria; Dino, Carolina Tanaka; Raboni, Sônia Mara; Sobieray, Narcizo Leopoldo Eduardo da Cunha; Carvalho, Newton Sérgio de

doi:10.1515/jpm-2021-0173

Cited by 3 publications

(3 citation statements)

References 19 publications

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“… 19 In Brazil, of 195 pregnant women, 1.02% of them were diagnosed with COVID‐19 by RT–PCR tests, and 8.7% were diagnosed with serological tests. 20 These studies are in contrast with our results because we found a higher prevalence, but the pregnant number analyzed in this study was lower in comparison with other study in Mexico City. 21 , 22 More studies are needed to determine the prevalence of COVID‐19 in pregnant women, because there are only few reports which show the pregnant women prevalence with SARS‐CoV‐2.…”

Section: Discussioncontrasting

confidence: 99%

“…In northern California, a COVID‐19 prevalence of 2.5% was found in pregnant women 19 . In Brazil, of 195 pregnant women, 1.02% of them were diagnosed with COVID‐19 by RT–PCR tests, and 8.7% were diagnosed with serological tests 20 . These studies are in contrast with our results because we found a higher prevalence, but the pregnant number analyzed in this study was lower in comparison with other study in Mexico City 21,22 .…”

Section: Discussionmentioning

confidence: 99%

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Epidemiological and clinical characteristics of pregnant women and neonates with COVID‐19 in Northwest Mexico

León-Sicairos

Angulo-Zamudio

Pacheco‐Avila

et al. 2022

American J Rep Immunol

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Introduction:The SARS-CoV-2 virus, which causes COVID-19, has spread quickly worldwide, causing millions of cases and thousands of deaths. Some risk factors in the general population are related to the development of severe COVID-19 or death, but in pregnant women and neonates, the information is limited. Objective: To determine the epidemiological and clinical characteristics of pregnant women and neonates diagnosed with COVID-19 by RT-PCR and serological tests, and analyze the relationship between the influenza vaccination and COVID-19 symptoms in infected pregnant women in Sinaloa state. Methods: We collected samples from 116 pregnant women and 84 neonates from the Woment's Hospital of Sinaloa. They were diagnosed with COVID-19 by RT-PCR and serological tests (IgG), and sociodemographic, clinical and laboratory parameters were recorded.Results: A total of 11.2% (13/116) of the pregnant women were RT-PCR+, 25% (29/116) were IgG+ and 4.3% (5/116) were positive for both tests. Symptoms such as rhinorrhea (P = .04), cough (P = .02) and polypnea (P = .04) in pregnant women were related to COVID-19, also leukocyte index was higher in pregnant women with COVID-19 (P = .03), but the associations were lost after the Bonferroni correction.No laboratory parameters or underlying diseases were associated with COVID-19, and most infected pregnant women had mild cases. We found an association between the influenza vaccine and less common COVID-19 symptoms in pregnant women who were infected (P = .01). A total of 7.2% (6/84) of neonates were RT-PCR+, 35.7%

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Section: Discussioncontrasting

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Epidemiological and clinical characteristics of pregnant women and neonates with COVID‐19 in Northwest Mexico

León-Sicairos

Angulo-Zamudio

Pacheco‐Avila

et al. 2022

American J Rep Immunol

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“…The serological evaluation was mainly carried out at the time of hospitalization, at the time of delivery, or randomly during pregnancy. However, to our knowledge, this is the first study assessing maternal and neonatal outcomes in a population sampled both in the first trimester and in the perinatal period [ 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 ].…”

Section: Discussionmentioning

confidence: 99%

SARS-CoV-2 Seroconversion and Pregnancy Outcomes in a Population of Pregnant Women Recruited in Milan, Italy, between April 2020 and October 2020

Accurti

Gambitta

Iodice

et al. 2022

IJERPH

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The possible link between SARS-CoV-2 infection and adverse pregnancy outcomes has so far demonstrated heterogeneous results in terms of maternal, fetal, and neonatal complications. We aim to investigate the correlation between SARS-CoV-2 seroconversion and/or neutralization titer and pregnancy outcomes. We analyzed a population of 528 pregnant women followed up from the first trimester of gestation until delivery. For each woman, we collected a first blood sample between 11 and 13 weeks of gestation and a second sample in the perinatal period (between peripartum and puerperium) to assess the presence of SARS-CoV-2 antibodies and/or microneutralization titer (MN titer). Data on pregnancy outcomes (gestational age at delivery, preterm birth before 34 weeks, hypertensive disorders, gestational diabetes, and abnormal fetal growth) were collected. We observed that serologic status per se is not associated with major pregnancy complications. On the contrary, the MN titer was associated with increased odds of gestational diabetes. Although we mainly reported asymptomatic SARS-CoV-2 infections and the absence of severe maternal and neonatal adverse outcomes, SARS-CoV-2 infection might challenge the maternal immune system and explain the moderate increase in adverse outcome odds.

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Seroprevalence of SARS-CoV-2 in Brazil: A systematic review and meta-analysis

Figueiredo

Tengan

Campos

et al. 2023

Clinics

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SARS-CoV-2 in asymptomatic pregnant women in South Brazil: RT-PCR and serological detection

Cited by 3 publications

References 19 publications

Epidemiological and clinical characteristics of pregnant women and neonates with COVID‐19 in Northwest Mexico

Epidemiological and clinical characteristics of pregnant women and neonates with COVID‐19 in Northwest Mexico

SARS-CoV-2 Seroconversion and Pregnancy Outcomes in a Population of Pregnant Women Recruited in Milan, Italy, between April 2020 and October 2020

Seroprevalence of SARS-CoV-2 in Brazil: A systematic review and meta-analysis

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