SARS-CoV-2 placentitis – report of two cases and review of the literature

Abstract

Covid-19 disease caused by severe acute respiratory syndrome 2 coronavirus (SARS-CoV-2) continues to be a global public health problem. Since the pandemic outbreak in early 2020, a number of cases have been reported in pregnant women whose infection has led to severe complications including preterm birth, miscarriage, intrauterine growth restriction or intrauterine fetal demise. The results of the current studies suggest that the transplacental transmission of infection from mother to fetus is a rare event and that the complications listed above are more likely due to damage of placental tissue. In this article, we describe two cases of SARS-CoV-2 placentitis with special consideration to the morphology and differential dia gnosis of this newly defined entity. Key words: placenta – covid-19 – SARS-CoV-2 – placentitis – histiocytic intervillositis

Therapeutic Management of Rare Primary Ovarian Neoplasms: Carcinosarcoma, Leiomyosarcoma, Melanoma and Carcinoid

“…Insular is described as the most common type, but was not observed in the analyzed group [51,52]. PCO is most common in peri-and postmenopausal women [53]. The mean age among the patients was 45.5 years.…”

“…Carcinoid can be asymptomatic [53,61] as well as with the presentation of symptoms. The cause of symptom presentation may be the presence of a tumor in the pelvis and its effect on surrounding tissues, but also the effect of specific substances produced by tumor cells, or the presence of metastases.…”

“…Hence, it is referred to as a specific type of mature teratoma. Indeed, 16 patients had a mature teratoma component in their tumor [47][48][49]51,53,63,65,66,[69][70][71][72][73]. It should be mentioned that there have been cases of strumal carcinoid without the presence of the teratoma, as well as the teratoma component present in histological types other than strumal.…”