SARS-CoV-2 Seroprevalence and Accuracy Diagnostic Evaluation During a Covid-19 Outbreak in a Major Penitentiary Complex in Brazil, June-July 2020: A Population-Based Study

Background People in prison are at increased risk of SARS-CoV-2 infection due to overcrowding and challenges in implementing infection prevention and control measures. We examined the seroprevalence of SARS-CoV-2 and associated carceral risk factors among incarcerated adult men in Quebec, Canada. Methods We conducted a cross-sectional seroprevalence study in 2021 in three provincial prisons, representing 45% of Quebec’s incarcerated male provincial population. The primary outcome was SARS-CoV-2 antibody seropositivity (Roche Elecsys® serology test). Participants completed self-administered questionnaires on sociodemographic, clinical, and carceral characteristics. The association of carceral variables with SARS-CoV-2 seropositivity was examined using Poisson regression models with robust standard errors. Crude and adjusted prevalence ratios (aPR) with 95% confidence intervals (95%CI) were calculated. Results Between January 19 and September 15, 2021, 246 of 1,100 (22%) recruited individuals tested positive across three prisons (range 15–27%). Seropositivity increased with time spent in prison since March 2020 (aPR 2.17, 95%CI 1.53–3.07 for “all” vs. “little time”), employment during incarceration (aPR 1.64, 95%CI 1.28–2.11 vs. not), shared meal consumption during incarceration (“with cellmates”: aPR 1.46, 95%CI 1.08–1.97 vs. “alone”; “with sector”: aPR 1.34, 95%CI 1.03–1.74 vs. “alone”), and incarceration post-prison outbreak (aPR 2.32, 95% CI 1.69–3.18 vs. “pre-outbreak”). Conclusions The seroprevalence of SARS-CoV-2 among incarcerated individuals was high and varied between prisons. Several carceral factors were associated with seropositivity, underscoring the importance of decarceration and occupational safety measures, individual meal consumption, and enhanced infection prevention and control measures including vaccination during incarceration.

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Seroprevalence and Risk Factors for Severe Acute Respiratory Syndrome Coronavirus 2 Among Incarcerated Adult Men in Quebec, Canada, 2021

Kronfli

Dussault

Maheu‐Giroux

et al. 2022

Clinical Infectious Diseases

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SARS-CoV-2 Seroprevalence and Accuracy Diagnostic Evaluation During a Covid-19 Outbreak in a Major Penitentiary Complex in Brazil, June-July 2020: A Population-Based Study

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Seroprevalence and Risk Factors for Severe Acute Respiratory Syndrome Coronavirus 2 Among Incarcerated Adult Men in Quebec, Canada, 2021

Seroprevalence and Risk Factors for Severe Acute Respiratory Syndrome Coronavirus 2 Among Incarcerated Adult Men in Quebec, Canada, 2021

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