2024
DOI: 10.21203/rs.3.rs-3831042/v1
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SARS-CoV-2 vaccination during pregnancy enhances hippocampal neurogenesis and working memory in offspring through IFN-gamma and CX3CR1-dependent mechanisms

Fangfang Qi,
Zhibin Yao

Abstract: The worldwide Coronavirus disease 2019 (COVID-19) pandemic affects the world, and prenatal COVID-19 infection is associated with severe adverse outcomes. Thus, both for safety and immunogenicity, the COVID-19 vaccination is strongly recommended for pregnant women. Specifically, this study examines how maternal COVID-19 vaccination affects postnatal physical development, neurogenesis, and behavior in pups. We successfully detected a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific antibody … Show more

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