SAT-406 Rituximab versus Cyclophosphamide as First Sparing Agent in Childhood Frequently relapsing and Steroid Dependent Nephrotic Syndrome

Abstract

We observed that Breg populations in treatment-naïve LN weresignificantly reduced compared to HC and increased significantly withimmunosuppression. Responders had a trend toward increase in Bregs over time, whereas non-responders did not.