Keywords:Fission chamber BR2 DEMO IFMIF Uncertainty cross-sections A comprehensive study is performed in order to assess the pertinence of fission chambers coated with different fissile materials for high neutrón flux detection. Three neutrón scenarios are proposed to study the fast component of a high neutrón flux: (i) high neutrón flux with a significant thermal contribution such as BR2, (ii) DEMO magnetic fusión reactor, and (iii) IFMIF high flux test module.In this study, the inventory code ACAB is used to analyze the following questions: (i) impact of different deposits in fission chambers; (ii) effect of the irradiation time/burn-up on the concentration; (iii) impact of activation cross-section uncertainties on the composition of the deposit for all the range of burn-up/irradiation neutrón fluences of interest. The complete set of nuclear data (decay, fission yield, activation cross-sections, and uncertainties) provided in the EAF2007 data library are used for this evaluation.