The analysis have been presented to observe the optimized flow of Casson nanofluid conveying the applications of external heat generation and mixed convection features. The problem is further influenced by chemical reactive species with order one. The significant of Bejan number is evaluated. A vertically moving with convective heat phenomenon endorsed the flow. The modeled problem is reflected in terms PDE’s which are further simplifies with dimensionless form. The analytical outcomes have been established with implementation of Laplace technique. The graphical impact conveying the different parameters is assessed. The insight of skin friction and Nusselt number is observed via various curves. It is observed that entropy generation enhanced due to porosity parameter and magnetic number. With increasing Casson fluid parameter, the entropy generation decrease. Moreover, the Bejan number decreases for chemical reaction constant.