We integrate a Denoising Autoencoder (DAE) into an Estimation of Distribution Algorithm (EDA) and evaluate the performance of DAE-EDA on several combinatorial optimization problems. We asses the number of fitness evaluations and the required CPU times. Compared to the state-of-the-art Bayesian Optimization Algorithm (BOA), DAE-EDA needs more fitness evaluations, but is considerably faster, sometimes by orders of magnitude. These results show that DAEs can be useful tools for problems with low but non-negligible fitness evaluation costs.