-CFD modeling for an internal loop airlift reactor is developed for different superficial gas velocities, ranging from 0.015 to 0.073 m/s. Based on the presence of gas bubbles in the downcomer, three regimes can be generally classified as: no gas bubbles (I), stagnation of gas bubbles (II), and recirculation of gas bubbles into the riser (III). The aim of the study is to carefully investigate the regime transition from II to III by considering the gas distribution. In regime II, the CFD simulation results show that the gas holdup difference between the riser and the downcomer remains constant. Due to the transition from regime II to III, the gas holdup difference sharply increases and the ratio of gas holdup in the downcomer and riser changes between the two regimes. At a superficial gas velocity slightly lower than that of the transitional regime, a small amount of gas is dragged to the riser, while the behavior of the regime is similar to regime II. The computational results show that CFD can be used as an effective tool to provide information on the details of the transition regime in internal loop airlift reactors.