2006
DOI: 10.1055/s-2006-923835
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Scaling Submaximal Exercise Cardiac Output and Stroke Volume: The HERITAGE Family Study

Abstract: IntroductionPhysiological variables are often scaled or normalized to account for differences in body size. The use of scaling is important in comparing individuals against a standard or to other individuals or groups differing in body size, investigating the longitudinal effects of growth, and examining relationships between physiological variables and performance.Traditionally, cardiac output (Q) and stroke volume (SV) have been scaled relative to body surface area (BSA [m 2 ], ratio scaling) to create size-… Show more

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Cited by 11 publications
(9 citation statements)
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“…VO 2max (15) was expressed as liters per minute (L * min −1 ) and calculated per kilogram of body weight (mL * kg −1 * min −1 ) (15) and body weight raised to the power of 0.75 (mL * kg −0.75 * min −1 ) (16‐19). The VO 2max test was performed as an individualized incremental treadmill test on a Woodway PPS 55 Plus (WOODWAY GmbH, Weil am Rhein, Germany).…”
Section: Methodsmentioning
confidence: 99%
“…VO 2max (15) was expressed as liters per minute (L * min −1 ) and calculated per kilogram of body weight (mL * kg −1 * min −1 ) (15) and body weight raised to the power of 0.75 (mL * kg −0.75 * min −1 ) (16‐19). The VO 2max test was performed as an individualized incremental treadmill test on a Woodway PPS 55 Plus (WOODWAY GmbH, Weil am Rhein, Germany).…”
Section: Methodsmentioning
confidence: 99%
“…Allometric scaling of submaximal exercise cardiac output and stroke volume produced size-independent measures of cardiac output and stroke volume and normalized submaximal cardiac output and stroke volume between sexes in the Health, Risk Factors, Exercise Training, and Genetics (HERITAGE) family study cohort, whereas ratiometric methods did not. 53 In premenarchal girls, allometric scaling of V O 2 max eliminated the effects of body size, whereas ratiometric scaling methods did not. 54 Similarly, in athletes, the associations between body size and allometrically scaled V O 2 max were minimal in cross-sectional 49 and longitudinal 50,51 studies, whereas significant correlations between body size and unscaled V O 2 max were observed.…”
Section: Evidence For Allometric Scaling Of Cardiovascular Functionmentioning
confidence: 98%
“…VO 2max expressed relative to body weight (mL·kg − 1 ·min − 1 ) has been shown to underestimate CRF in heavy subjects, and overestimate CRF in light subjects. VO 2max scaled relative to the body weight raised to the power of 0.75 (mL·kg -0.75 ·min − 1 ) has eliminated the differences [2124]. In order to account for VO 2max related to body size and weight, the results of VO 2max were allometrically scaled to mL·kg -0.75 ·min − 1 .…”
Section: Methodsmentioning
confidence: 99%