Scanning Electron Microscopic Changes in Habronema Muscae After in Vitro Exposure to Plant Extract (Verbesina Alternifolia)

Abdel-Wahab, A.; Abdel-Maogood, S. Z.; Mahdy, And O A

doi:10.21608/jesp.2017.77965

Cited by 3 publications

(1 citation statement)

References 28 publications

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“…Generally, the nematodes cuticle is active and in charge of selective nutrients absorption and regulation of osmosis, which was known to be the primary entry channel and primary site of action of nematicidal drugs (Abdel-Wahab et al, 2017). So, the erosive changes and deformities could be attributed to the passive diffusion of the drugs through the cuticle.…”

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confidence: 99%

Evaluation of Olibanum Extract Activity Against Trichinella Spiralis Adults and Larvae: In Vitro Study

Shendi

Matar²

2022

Journal of the Egyptian Society of Parasitology

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Trichinellosis is a globally re-emerging parasitic disease. The available current treatments are more or less not effective especially for larvae with many drawbacks. Consequently, appropriate natural treatment is needed. The present study evaluated the in-vitro anthelminthic effects of Olibanum (OL) extract against Trichinella spiralis adults and larvae. Adults and muscle larvae were incubated with OL extract at concentrations of 10, 25, 50, 100, & dium. The histopathological changes and mortality both stages were assessed by using scanning electron microscopy (SEM). The OL extract showed significant anthelminthic activity against adult and larval stages. The maximum and the earliest inhibitory effect were with 150 (100% mortality at 36hr incubation) for both stages. However, a concentration of 100 showed prolonged incubation time (48hr). Difference between both concentrations was signi-0.5). Besides, T. spiralis adults and larvae incubated with OL extract at concentrations of 100 &150 histopathological changes in the form of cracks, blebs and areas of degenerative changes with loss of normal annulations.

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Section: Introductionmentioning

confidence: 99%

Evaluation of Olibanum Extract Activity Against Trichinella Spiralis Adults and Larvae: In Vitro Study

Shendi

Matar²

2022

Journal of the Egyptian Society of Parasitology

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Unravelling the anthelmintic bioactives from Jasminum grandiflorum L. subsp. Floribundum adopting in vitro biological assessment

Hussein

El-Shiekh

Saber

et al. 2021

Journal of Ethnopharmacology

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Habronematidosis in Equids: Current Status, Advances, Future Challenges

et al. 2020

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Over the past few decades, among equine parasitoses caused by gastrointestinal nematodes, habronematidosis has been discontinuously studied worldwide. Habronematidosis is a parasitic disease distributed all over the world. It is caused by Habronema microstoma, Habronema muscae, and Draschia megastoma (Spirurida, Habronematidae), and it is maintained in the environment by muscid flies which act as intermediate hosts. At larval and adult stages these species live in the stomach of domestic and wild equids. However, the larvae can also be found on the skin, causing lesions known as "summer sores", and occasionally on other body areas, such as ocular and genital mucosa (muco-cutaneous habronematidosis) and lung, liver, brain parenchyma. Depending on the parasite's developmental stage and localization site, clinical signs vary from mild to severe. Habronematidosis is responsible for significant economic losses, mostly when sport horses are affected, because their performances are impaired and the infection can be unaesthetic. We used three on-line databases for searching the articles on habronematidosis according to the selected inclusion criteria; a total of 250 contributions, published between 1911 and 2020 were analyzed. This review summarizes the key features of pathogenesis, epizootiology, diagnosis, treatment, and control of habronematidosis, and highlights the current knownledge about its geographical distribution and spread. Anthelmintic drugs are the most widely-used tools against habronematidosis; given the known risk of anthelmintic resistance in some nematodes affecting horses, this aspect should also be explored for habronematidosis. Dedicated research is essential to fill gaps of knowledge and increase the understanding of habronematidosis to maximize equine health, reduce economic losses and sanitary impact associated with this parasitic infection.

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Scanning Electron Microscopic Changes in Habronema Muscae After in Vitro Exposure to Plant Extract (Verbesina Alternifolia)

Cited by 3 publications

References 28 publications

Evaluation of Olibanum Extract Activity Against Trichinella Spiralis Adults and Larvae: In Vitro Study

Evaluation of Olibanum Extract Activity Against Trichinella Spiralis Adults and Larvae: In Vitro Study

Unravelling the anthelmintic bioactives from Jasminum grandiflorum L. subsp. Floribundum adopting in vitro biological assessment

Habronematidosis in Equids: Current Status, Advances, Future Challenges

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