Scanning Super/Ultrapulsed CO2 Laser Efficacy in Laryngeal Malignant Lesions

Dallari, Stefano; Giannoni, Luca; Filosa, Alessandra

doi:10.3390/medicina58020200

Cited by 3 publications

(3 citation statements)

References 23 publications

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“…This is in contrast with previous observation that described CO 2 laser treatments with no colposcopic magnification unable to treat extensive areas worrying patients [11]. The Scanning Micromanipulator is of the same generation and technology of those used nowadays in ENT or neurosurgical prodedures [14][15], the scanner fastly and precisely moves on the tissue a microspot of 250mm of diameter focused by the micromanipulators' zoom at 300mm EFL (the working distance of the colposcope) creating shapes suited for cutting and ablation: Hexagons, circles, lines. This allows to deliver the energy to the tissue controlling in a repeatable way depth of ablation and limiting the thermal damage.…”

Section: Moreover Us Centers For Disease Control and Preventionmentioning

confidence: 76%

Colposcopic-Magnified Scan-Aided CO2 Laser Vaporization for Genital Warts in Pregnancy: a Propsective Descriptive Evaluation of Safety in a Tertiary Care Obstetrical Hospital

2023

J Surg

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Objectives: Genital warts caused by infection with LOW RISK HPV may infect newborns risking to develop Juvenile Onset Recurrent Respiratory Papillomatosis (JORRP). No clear guidelines are available to manage genital warts in pregnancy. Although cesarean section is not recommended, almost 20% of warty pregnant patients still undergo cesarean section due to genital warts in labour. Aim was to show efficiency of a minimally invasive laser technique to treat warts in pregnancy.Methods: A prospective study on all patients of Authors' obstetrical ward diagnosed from 2014 to 2019 with genital warts during pregnancy and submitted to Colposcopic Magnified Scan-aided CO 2 Laser Vaporization (CMSLV) was conducted. The aim of every laser session was no residual disease. Patients were submitted to colposcopy every three weeks until delivery to assess and treat eventual relapse. Laser outcome was evaluated in term of number of treatments per pregnancy. Rates of preterm labour, cesarean section and indication to cesarean section, performed episiotomy, occurred perineal tears were collected and compared to rates of the obstetrical population delivering at Authors' clinic in 2021.Rate of breastfeeding was collected as index of mother wellbeing. Infants were followed for three years after birth at neonatologic unit to check for JORRP.Results: 221 pregnant women were enrolled: 29.8 % needed multiple-site laser vaporization, 86% needed a singular procedure, while 14% multiple treatments. 8.1% cesarean section were performed but only 0.9% because of genital warts. No statistically difference in term of obstetrical outcomes were observed among patients who underwent single or multiple procedures. CMSLV didn't represent a major risk factor for cesarean section or operative procedures when compared to a third level care unit population risk factors). 78.3% of newborns were exclusively breastfed. No JORRP cases were registered among the case series' infants.Conclusions: CMSLV minimizes vaporized areas, can be performed in outpatient setting with local anesthesia up to the term of gestation, reduces the risk of chosing cesarean section as JORRP preventing option under 1% and preserves obstetrical outcomes and mothers'wellbeing.

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Section: Moreover Us Centers For Disease Control and Preventionmentioning

confidence: 76%

Colposcopic-Magnified Scan-Aided CO2 Laser Vaporization for Genital Warts in Pregnancy: a Propsective Descriptive Evaluation of Safety in a Tertiary Care Obstetrical Hospital

2023

J Surg

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“…Scanning-aided “free beam” laser surgery is the only technology that enables the surgeon to control the ablation depth and the thermal effect for each scanning passage. Moreover, scanning technology has already been intensively used in many fields of surgery like Gynecology, Colposcopy, Ears-Nose-Throat, Neurosurgery, and General Surgery (i.e., Proctology and Wound Healing) [ 26 , 27 , 28 , 29 , 30 ]. The CO 2 laser can also be delivered using a flexible hollow fiber (i.e., Smartxide2 TRIO System, DEKA, Calenzano, Italy).…”

Section: Methodsmentioning

confidence: 99%

Superficial Peritoneal Endometriosis Vaporization Using a CO2 Laser: A Long-Term Single-Center Experience

Di Michele,

Bramante,

Angioni

et al. 2024

JCM

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Background: The validation of laser usage during laparoscopic procedures, notably by Camran Nezhat in the late 1980s, has been significant. Lasers offer precision and depth control in tissue vaporization without bleeding. Surgical intervention remains central in managing endometriosis-associated pain and infertility, especially for patients unresponsive to hormonal therapy. Methods: This retrospective cohort study included 200 patients with superficial peritoneal endometriosis (SPE) who underwent laparoscopic laser vaporization. Surgery was performed using a CO2 laser, and histological confirmation of endometriosis was obtained for all cases. Pain scores and SF-36 questionnaire domains were assessed preoperatively and postoperatively. Fertility outcomes were evaluated among patients desiring pregnancy. Results: Significant improvements in pain score and SF-36 questionnaire domains were observed postoperatively (p-value < 0.01), indicating enhanced quality of life. Among infertile patients with an active desire for pregnancy, surgical treatment showed an overall pregnancy rate after surgery of 93.7% (p-value < 0.01), including 75.7% natural pregnancies and 24.3% IVF. Laser vaporization enabled precise lesion removal with minimal tissue damage, short operative time, and minimal blood loss. Conclusions: Laparoscopic laser vaporization is an effective treatment for SPE, offering pain relief, improved quality of life, and favorable fertility outcomes. Further research is needed to validate these results in terms of pain control and fertility.

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“…Scanning-aided "free beam" laser surgery is the only technology that enables the surgeon to control the ablation depth and the thermal effect for each scanning passage. Moreover, scanning technology has already been intensively used in many fields of surgery like Gynecology, Colposcopy, Ears-Nose-Throat, Neurosurgery, and General Surgery (i.e., Proctology and Wound Healing) [24][25][26][27][28]. The CO2 laser can also be delivered by flexible hollow fiber (i.e., Smartxide2 TRIO System).…”

Section: Surgical Proceduresmentioning

confidence: 99%

Superficial Peritoneal Endometriosis Vaporization Using a CO2 Laser: a long-term single-center experience.

Di Michele,

Bramante,

Angioni

et al. 2024

Preprint

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Scanning Super/Ultrapulsed CO2 Laser Efficacy in Laryngeal Malignant Lesions

Cited by 3 publications

References 23 publications

Colposcopic-Magnified Scan-Aided CO2 Laser Vaporization for Genital Warts in Pregnancy: a Propsective Descriptive Evaluation of Safety in a Tertiary Care Obstetrical Hospital

Colposcopic-Magnified Scan-Aided CO2 Laser Vaporization for Genital Warts in Pregnancy: a Propsective Descriptive Evaluation of Safety in a Tertiary Care Obstetrical Hospital

Superficial Peritoneal Endometriosis Vaporization Using a CO2 Laser: A Long-Term Single-Center Experience

Superficial Peritoneal Endometriosis Vaporization Using a CO2 Laser: a long-term single-center experience.

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