Scedosporium apiospermum infection presenting as a mural urinary bladder mass and focal peritonitis in a Border Collie

Abstract

Scedosporium apiospermum is an opportunistic mold that is an emerging disease in humans and animals. This report describes a case of S. apiospermum infection inciting a mural urinary bladder mass and focal peritonitis in a dog that had a history of multiple traumatic events several years prior. For diagnosis, culture followed by MALDI-ToF, PCR, and sequencing was performed to accurately identify the species. Susceptibility testing was also performed due to the inherent resistance of S. apiospermum to numerous antifungal agents.

Multiple intra-abdominal fungal granulomas caused by Scedosporium apiospermum effectively treated with voriconazole in a Golden Retriever

“…Therefore, the differentiation of these fungi is clinically important for prognostic prediction. In general, reliable culture identification based on fungal morphological differences is considered difficult to identify species [ 12 ]. Therefore, reliable species identification using molecular biological techniques is recommended.…”

The Bee Gut Microbiota: Bridging Infective Agents Potential in the One Health Context

“…and Scedosporum spp. are relevant for their ability to provoke mycosis at various levels of severity in a broad spectrum of animals, ranging from bovines and horses to dogs and cats [35][36][37][38]. More common is the identification of Ascosphaera apis, the causal agent of chalkbrood disease, one of the most significant fungal infections of the honey bees [39], along with the stonebrood disease, which is sustained by Aspergillus spp.…”